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" 10 drugs that could stop Ebola "

FIERCE BOIOTECH RESEARCH                       Oct. 14, 2014
By Emily Mullin

Before the current Ebola outbreak, the virus had only appeared in Africa in fits and starts since its discovery in 1976, receding back into the jungle almost as quickly as it arrived. This relative rarity and the swiftness with which the disease kills its victims has, up until now, made Ebola an unattractive--not to mention daunting--prospect for drug developers. As a result, no approved drugs or vaccines against Ebola exist.

...the current situation in West Africa... has prompted the World Health Organization to call on international government agencies and the pharmaceutical industry to work together to speed up the development of promising therapies for experimental use for those most at risk of contracting the disease, which causes severe hemorrhagic fever.

Now, a handful of players are racing to get a treatment or vaccine to patients as quickly as possible, even though these drugs remain largely untested in humans.... 

Here is a list of organizations that are in the global spotlight right now with their investigational Ebola program

See full story and list

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Facebook Founder Mark Zuckerberg Kicks in $25 Million for Ebola

NBC NEWS                                                            OCT. 14, 2014

Facebook founder Mark Zuckerberg and his wife announced Tuesday they are donating $25 million to the U.S. Centers for Disease Control foundation to fight the Ebola crisis that has killed more than 4,440 people in west Africa.

"We need to get Ebola under control in the near term so that it doesn't spread further and become a long term global health crisis that we end up fighting for decades at large scale, like HIV or polio," Zuckerberg, who is worth $32 billion, said in a Facebook post. "We believe our grant is the quickest way to empower the CDC and the experts in this field to prevent this outcome."

The health agency has hundreds of staffers working on Ebola and has sent more than 100 experts to the virus zone — Liberia, Guinea, Sierra Leone and Nigeria. The CDC foundation collects funds for supplies, such as personal protective equipment, ready-to-eat meals, generators, vehicles and motorcycles, and thermal scanners to detect fever.

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The reassuring news in the Texas Ebola cases


By Todd C. Frankel                         October 14

....The Dallas nurse, 26-year old Nina Pham,who helped treat Thomas Eric Duncan, the Liberian man who was the first person diagnosed with the dreaded disease in the United States became the first – and so far only – person infected by Duncan. In the wake of her infection, U.S. health officials have pledged to review how future Ebola cases are handled.

But the case is also noteworthy for another, potentially positive reason: Nearly 50 people were exposed to Ebola before the nurse, and none of them has been diagnosed with the disease.

This group of neighbors, family members and first responders are being watched carefully by health authorities. They had some degree of close contact with Duncan during the four-day period when he was contagious – from when he started showing Ebola symptoms on Sept. 24 to when the hospital finally admitted him on Sept. 28. They didn’t take any Ebola-specific precautions. They didn’t know he was infected.... Yet, so far, they have not gotten sick. And their 21-day Ebola incubation period started before Pham’s.

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Tweets About Ebola -

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Family Identifies Ebola Patient - by marjorie Owens - October 13, 2014

DALLAS — A Dallas nurse diagnosed with the Ebola virus over the weekend is a former Texas Christian University student identified by a family member as 26-year-old Nina Pham.

The family reached out to News 8 Monday morning and shared an image of the nurse who grew up in Fort Worth.

A health care worker at Texas Health Presbyterian Hospital Dallas, Pham became infected while treating Thomas Eric Duncan, who died from the virus days before the nurse's diagnosis.


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Ebola Vaccine Would Likely Have Been Found By Now If Not For Budget Cuts: NIH Director


By Sam Stein                                                              Updated Oct. 13 ,2014

BETHESDA, Md. -- As the federal government frantically works to combat the Ebola outbreak in West Africa, and as it responds to a second diagnosis of the disease at home, one of the country's top health officials says a vaccine likely would have already been discovered were it not for budget cuts.

Dr. Francis Collins, the head of the National Institutes of Health, said that a decade of stagnant spending has "slowed down" research on all items, including vaccinations for infectious diseases. As a result, he said, the international community has been left playing catch-up on a potentially avoidable humanitarian catastrophe.

"NIH has been working on Ebola vaccines since 2001. It's not like we suddenly woke up and thought, 'Oh my gosh, we should have something ready here,'" Collins told The Huffington Post on Friday. "Frankly, if we had not gone through our 10-year slide in research support, we probably would have had a vaccine in time for this that would've gone through clinical trials and would have been ready."

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Hospitals should ‘think Ebola,’ CDC director says

CDC: U.S. has to rethink the way it addresses Ebola infection control

ASSOCIATED PRESS                                                            Oct. 13, 2014

By Connie Cass

DALLAS --Every hospital must know how to diagnose Ebola in people who have been in West Africa and be ready to isolate a suspected case, Tom Frieden, director of the Centers for Disease Control and Prevention, said Monday.

He said the CDC is working to improve protections for hospital workers after a nurse caring for an Ebola patient in Dallas became the first person to become infected with the disease inside the U.S.

‘‘We have to rethink the way we address Ebola infection control,’’ Frieden said, ‘‘because even a single infection is unacceptable.’’

The CDC is scrambling to interview all staff of the Dallas hospital who could have been exposed to the patient, a Liberian man who became sick after traveling to the United States and died at the hospital. Anyone at risk will be monitored, he said.

‘‘We need to consider the possibility that there could be additional cases, particularly among the health care workers who cared for the index patient’’ — the Liberian man — ‘‘when he was so ill,’’ Frieden said.

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Scroll down for the stories and link to CDC check list


NEW YORK TIMES                   Oct. 13, 2014
By Pam Belluck

The Centers for Disease Control and Prevention is taking new steps to help hospital workers protect themselves, providing more training and urging hospitals to run drills to practice dealing with potential Ebola patients.

In response to the news that a health care worker in Dallas had contracted Ebola, a spokeswoman said the agency would also issue more specific instructions and explanations for putting on and removing protective equipment and would urge nurses and doctors to enlist a co-worker or “buddy” to watch them do so....

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Obama orders CDC probe in 2nd Dallas Ebola case to move ‘as expeditiously as possible’


                                    October 12, 014 

President Obama received two briefings on the diagnosis of a second Ebola case in Dallas, according to White House officials, and Sen. John McCain (R-Ariz.) urged the president to appoint a "czar" to coordinate the administration's response to the disease.

Obama was briefed Sunday morning by Lisa Monaco, who serves as assistant to the president for homeland security and counterterrorism and is overseeing the interagency response to the disease. Later, according to White House officials, Obama also discussed the situation with Health and Human Services Secretary Sylvia Burwell.

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Ebola Protocol Was Likely Breached In Texas, Medical Officials Say

HUFFINGTON  POST                     Oct.12, 2014      11:08 AM

The Texas health care worker who contracted Ebola after providing care for an infected patient likely breached safety protocols, health officials said Sunday.

"Certainly there has to have been an inadvertent, innocent breach of the protocol of taking care of the patient within the personal protective equipment -- that extremely rarely happens," Dr. Anthony Fauci, the head of the National Institute of Allergy and Infectious Diseases, told Martha Raddatz on ABC's "This Week" Sunday. "We've been taking care of Ebola patients since 1976. Groups like Doctors Without Borders who do that almost never have an infection, because of the experience of doing this."

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