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Yellow Fever Deaths Climb to 60 in Brazil Outbreak

           

Aedes Aegypti mosquito. SHUTTERSTOCK KOMUNIKA ONLINE

CLICK HERE - CDC - Yellow Fever in Brazil

en.tempo.co - February 5, 2017

TEMPO.CO, Rio de Janeiro - The Brazilian government announced Friday that the number of confirmed deaths caused by a yellow fever outbreak has reached 60, while 87 more suspicious deaths are being investigated.

In a statement, the Health Ministry said that 53 of the deaths had come in the state of Minas Gerais, where the outbreak started before spreading to other states. Four people have died in Espirito Santo and three more in the state of Sao Paulo.

Since the start of the outbreak, 150 deaths were potentially attributed of yellow fever, 60 of which have been confirmed, 87 are still under investigation and three have been eliminated.

In total, 921 people have been suspected of being infected, 804 of which happened in Minas Gerais. 702 are being investigated, 161 have been confirmed and 58 have been ruled out.

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Miami Doctors Publish Study of First Locally-Acquired Zika Transmission

This is a rash on patient's stomach.
Credit: The New England Journal of Medicine

submitted by Alicia Juarrero

sciencedaily.com - January 12, 2017

Source: University of Miami Miller School of Medicine

Summary: Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians has published a case study describing in detail the nation's first locally-transmitted case of Zika.

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CLICK HERE - NEJM - Cutaneous Eruption in a U.S. Woman with Locally Acquired Zika Virus Infection

 

 

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We Are Grossly Unprepared for Major Outbreaks

submitted by Alicia Juarrero

           

CLICK HERE - The BMJ - Post-Ebola reforms: ample analysis, inadequate action

CLICK HERE - Post-Ebola reforms: ample analysis, inadequate action (8 page .PDF report)

globalbiodefense.com - January 26, 2017

The world remains “grossly underprepared” for outbreaks of infectious disease, which are likely to become more frequent in the coming decades, warn a team of international experts in The BMJ.

They reviewed reports on the recent Ebola virus outbreak in West Africa and say better preparedness and a faster, more coordinated response could have prevented most of the 11,000 deaths directly attributed to Ebola and also the broader economic, social, and health crises that ensued.

. . . a research team, led by Suerie Moon at the Graduate Institute of International and Development Studies in Geneva, synthesized seven major post-Ebola reports and laid out the key problems and recommendations they highlighted.

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Highest Radiation Reading Since 3/11 Detected at Fukushima No. 1 Reactor

           

Based on image analysis, a two-meter hole has been found in the metal grate under a pressure vessel in reactor No. 2's containment vessels at the Fukushima No. 1 nuclear power plant. | TOKYO ELECTRIC POWER COMPANY HOLDINGS INC. / VIA KYODO

japantimes.co.jp - KYODO, STAFF REPORT

The radiation level in the containment vessel of reactor 2 at the crippled Fukushima No. 1 power plant has reached a maximum of 530 sieverts per hour, the highest since the triple core meltdown in March 2011, Tokyo Electric Power Co. Holdings Inc. said.

Tepco said on Thursday that the blazing radiation reading was taken near the entrance to the space just below the pressure vessel, which contains the reactor core.

The high figure indicates that some of the melted fuel that escaped the pressure vessel is nearby.

At 530 sieverts, a person could die from even brief exposure, highlighting the difficulties ahead as the government and Tepco grope their way toward dismantling all three reactors crippled by the March 2011 disaster.

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Suspected Yellow Fever Outbreak in Brazil

According to the World Health Organization, relatively low vaccination coverage in the state of Minas Gerais “could favor the rapid spread of the disease.”

           

WIKIMEDIA, CDC

CLICK HERE - WHO - Yellow Fever - Brazil

the-scientist.com - by Tracy Vence - January 19, 2017

More than 120 people may have been infected with the Yellow Fever virus in Brazil since December, according to the World Health Organization (WHO). Thirty of them have died. In a January 13 report, the WHO noted that relatively low vaccination coverage in one region where the virus is suspected to be spreading, in the state of Minas Gerais, “could favor the rapid spread of the disease.”

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Donors and Drug Makers Offer $500 Million to Control Global Epidemics

           

A child born with microcephaly caused by the Zika virus, during an evaluation at Fundação Altino Ventura in Recife, Brazil. A group of prominent donors announced Wednesday that they had raised almost $500 million for a new partnership to stop epidemics before they spiral out of control. Credit Adriana Zehbrauskas for The New York Times

nytimes.com - by DONALD G. McNEIL Jr. - January 18, 2017

Stung by the lack of vaccines to fight the West African Ebola epidemic, a group of prominent donors announced Wednesday that they had raised almost $500 million for a new partnership to stop epidemics before they spiral out of control.

The partnership, the Coalition for Epidemic Preparedness Innovations, will initially develop and stockpile vaccines against three known viral threats, and also push the development of technology to brew large amounts of vaccine quickly when new threats, like the Zika virus, arise.

With enough money and scientific progress, the strategy could bring a drastic change in the way the world tackles pandemics.

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DNA-Testing Smartphone Aims to Tackle Drugs Resistance

submitted by Alicia Juarrero

           

UCLA, STOCKHOLM UNIVERSITY AND UPPSALA UNIVERSITY

CLICK HERE - Nature Communications - Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy

bbc.com - by Leo Kelion - January 18, 2017

Scientists have built a DNA-analysing smartphone attachment that is a fraction of the cost of lab-based kit.

The creators of the phone-powered pathology microscope believe it could be mass produced for less than $500 (£406) a unit.

They say it could help doctors treat cancer, tuberculosis and other diseases more effectively than is sometimes possible in the developing world.

But a UK firm says it is developing a more advanced and cheaper alternative.

Details of the peer-reviewed project are published in the journal Nature Communications.

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A Woman Was Killed by a Superbug Resistant to All 26 American Antibiotics

           

The Klebsiella pneumoniae organism in a petri dish.  GARY CAMERON / REUTERS

CLICK HERE - STUDY - CDC - MMWR - Notes from the Field: Pan-Resistant New Delhi Metallo-Beta-Lactamase-Producing Klebsiella pneumoniae — Washoe County, Nevada, 2016

No Antibiotic In The U.S. Could Save This Woman. We Should All Be Worried.

This is one of the first cases of a pan-resistant infection in America.

huffingtonpost.com - by Anna Almendraia - January 13, 2017

The recent death of a woman in Reno, Nevada, from an infection resistant to every available kind of antibiotic in the U.S. highlights how serious the threat of antibiotic-resistant superbugs has become. 

Experts say that while cases of a bacteria resistant to all antibiotics are still extremely rare in the U.S., we should expect to see more in the future. 

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First Ebola-Related Death from Breast Milk Transmission Reported in Guinea

Sissoko D, et al. Clin Infect Dis. 2016;doi:10.1093/cid/ciw79.

CLICK HERE - STUDY -  Ebola virus persistence in breast milk after no reported illness: a likely source of virus transmission from mother to child

healio.com - January 10, 2017

Genomic analysis confirmed that the 2015 death of a 9-month-old Guinean infant from Ebola virus was the result of transmission through the breast milk of her asymptomatic mother, according to a recent case study.

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Ebola RNA Found Hiding in Healthcare Worker’s Lungs

           

WIKIMEDIA, HELLERHOFF

CLICK HERE - STUDY - Detection of Viral RNA in Tissues following Plasma Clearance from an Ebola Virus Infected Patient

A case study reports evidence of viral replication lingering in the respiratory tract of an infected person, even after their blood was Ebola free.

the-scientist.com - by Bob Grant - January 5, 2017

Ebola virus may linger and continue to replicate in the lungs of patients recovering from infection, even after viral RNA is no longer detectable in their bloodstreams, according to a case study published today (January 5) in PLOS Pathogens. . . .

 . . . Ippolito and his colleagues monitored the Ebola-infected patient, who was moved from West Africa to a hospital in Italy in 2015, over the course of their infection. They found viral RNA and other markers of viral replication in the patient’s lungs five days after such markers were no longer detectable in the blood.

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