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U.S. has stockpiled millions of doses of two smallpox vaccines, also effective against monkeypox. But the outbreaks so far are clustered in other countries.

As more than a dozen countries grapple with outbreaks of monkeypox, health officials worldwide are rushing to assess reserves of vaccines and treatments that may be needed to contain the spread.

The U.S. emergency stockpile holds two vaccines approved by the Food and Drug Administration that could be used to contain monkeypox, officials at the Centers for Disease Control and Prevention told reporters on Monday.

The stockpile contains more than 100 million doses of the original smallpox vaccine. But that vaccine is associated with side effects and shouldn’t be given to certain patients, including those who are immuno-compromised.

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