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EBOLA EPIDEMIOLOGY: Strategies for containing Ebola in West Africa

SCIENCE MAGAZINE                             Oct. 30, 2014

A study to assess the effectiveness of containment strategies, using a stochastic model of Ebola transmission between and within the general community, hospitals, and funerals, calibrated to incidence data from Liberia.


The ongoing Ebola outbreak poses an alarming risk to the countries of West Africa and beyond. To assess the effectiveness of containment strategies, we developed a stochastic model of Ebola transmission between and within the general community, hospitals, and funerals, calibrated to incidence data from Liberia. We find that a combined approach of case isolation, contact tracing with quarantine and sanitary funeral practices must be implemented with utmost urgency in order to reverse the growth of the outbreak. Under status quo intervention, our projections indicate that the Ebola outbreak will continue to spread, generating a predicted 224 (95% CI: 134 – 358) cases daily in Liberia alone by December, highlighting the need for swift application of multifaceted control interventions.

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Home> International Liberia Opens 1 of Largest Ebola Treatment Centers

In this photo taken Wednesday, Oct. 29, 2014, aid is offloaded to be used in the fight of the Ebola virus, as it arrives by air from America at the airport in Conakry, Guinea. No African countries are on the United Nations list of contributors to fight the Ebola epidemic, and angry legislators from Sierra Leone and Liberia got up to protest at a session on peace and security at the Pan-African Parliament in South Africa last "They said as far as they are concerned, nobody wants to talk about Ebola," said Jeggan Grey-Johnson, a governance expert. (AP Photo/ Youssouf Bah)

REUTERS                                                                                   Oct. 31, 2014
ByJonathan Paye-Layleh

MONROVIA, Liberia —Remembering those who have died in the world's deadliest Ebola outbreak, Liberia's president opened one of the country's largest Ebola treatment centers in Monrovia on Friday amid hopes that the disease is finally on the decline in this West African country.

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World Bank funding for Ebola fight hits $500 million

REUTERS                                                                                          Oct. 30, 2014

(GENEVA)- The World Bank pledged $100 million on Thursday to help recruit more foreign health workers in the fight against Ebola, taking its funding for the three worst-hit countries to more than half a billion dollars over the past three months.


People sit near a banner reading ''The Ministry of Agriculture, Dixinn Commune, Together to defeat Ebola,'' in Conakry, Guinea October 26, 2014.Credit: Reuters/Michelle Nichols

The latest tranche will go towards setting up a coordination hub to recruit, train and deploy qualified foreign health workers and support the three countries' efforts to isolate Ebola patients and bury the dead safely, the bank said.

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Genes Influence How Mice React to Ebola, Study Says In ‘Significant Advance’

NEW YORK TIMES                        Oct. 30, 2014

By Gina Kolata

Some people exposed to the Ebola virus quickly sicken and die. Others become gravely ill but recover, while still others only react mildly or are thought to be resistant to the virus. Now researchers working with mice have found that these laboratory animals, too, can have a range of responses to Ebola, and that in mice, the responses are determined by differences in genes.

Researchers at the University of Washington have been studying the Ebola virus in mice, and have found that the effects of the virus may be determined by genes.Video and photo by University of Washington.

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Ebola outbreak: UK aid ship docks in Sierra Leone

The Argus arrives with supplies and medical personnel to assist Serra Leone

 BBC                                                              Oct. 30, 2010

By AndrewHarding

FREETOWN, Sierra Leone--  A British Navy support ship ship has arrived in Sierra Leone to help deal with the deadly Ebola outbreak in the West African country.

Royal Fleet Auxiliary Argus is carrying food, medical equipment, three helicipeters and 32 pick-up trucks, to help keep hard-pressed Ebola treatment centres going.

Doctors, nurses and military personnel are also on board.

The BBC's Africa correspondent Andrew Harding said it would act as an offshore base for the aid effort. and described it as an "important moment".

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Ebola: Better Maps Could Have Helped Fight Virus

How Maps Could Help Fight Ebola

SKY NEWS                                             Oct. 0, 2014

By Tom Cheshire, Technology Correspondent

LONDON -- Better maps could have helped contain the deadly Ebola virus, according to Medecins Sans Frontieres.

Ivan Gaytan, technology advisor to MSF, told Sky News the disease is "preventable" and could have been "easier to contain" if there was more knowledge of the region.

He said: "In any country where Ebola or any other infectious disease arrives, if you already have a good map which actually reflects the way people describe geography, you set up your clinical activities to take that data in the first place in the right way."

MSF, also known as Doctors Without Borders, will launch a project next month called Missing Maps, which lets anyone, anywhere in the world, annotate maps to show dwellings and infrastructure.

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Ebola Virus Disease and the Need for New Personal Protective Equipment

Michael B. Edmond, MD, MPH, MPA1; Daniel J. Diekema, MD, MS1; Eli N. Perencevich, MD, MS

" is clear that reengineering of personal protecion equipment is required, both in US hospitals but more critically for the outbreak zones in Africa. The use of cumbersome PPE in the extreme heat and difficult working conditions of Ebola treatment centers in Africa places great stress on health care workers and limits the time they can spend providing patient care.

" A novel approach to PPE that provides an impermeable fluid barrier that is both more comfortable and easier to don and remove would be a substantial step forward.

"This will require new materials and designs. Indeed, the US Agency for International Development, White House Office of Science and Technology Policy, CDC, and US Department of Defense have recently announced a campaign to develop and test innovations for PPE in response to the Ebola outbreak."

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The whole world relies on this one U.S. company to fly Ebola patients

WASHINGTON POST                          Oct 28, 2014
By Josh Hicks
When it comes to transporting Ebola victims by air, the world relies on just one small U.S. company.

Phoenix Air has been using the isolation system below this aircraft to transport Ebola patients. (EPA/BRANDEN CAMP)

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Israeli firm ships inflatable tents for West Africa Ebola patients

Y YETNEWS                                        Oct. 27, 2014
Udi Etsion
An Israel icompany has developed and installed in Guinea special inflatable isolation tents to be used to house and isolate Ebola patients.

Special inflatable tent being used to fight Ebola

The inflatable tents have also been purchased for the treatment of Ebola patients by other countries on the continent, according to the Israeli company SYS Technologies, which specializes in the development of clean-air systems and mobile operating theaters. The company said the units can be constructed and shipped within two weels.

The units use a positive pressure technology to create an absolute clear and isolated environment and maintain the structure. The company has also developed an incubator-like stretcher for the safe transfer of patients to the isolation tents.

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Swiss Agency Approves Trial for Ebola Vaccine

ASSOCIATED PRESS                                 Oct. 28, 2014
  GENEVA-- The Swiss agency that regulates new drugs said Tuesday it has approved an application for a clinical trial with an experimental Ebola vaccine at the Lausanne University Hospital.

In this picture provided by the World Health Organization, a package of vials of the first shipment of the experimental vaccine VSE-EBOV is opened at the Geneva Cantonal hospital on Wednesday, Oct. 22, 2014. The World Health Organization (WHO) welcomes the donation by the government of Canada of 800 vials of an experimental candidate vaccine, VSV-EBOV, against Ebola virus disease. Clinical safety trials with this experimental Ebola vaccine have already begun in healthy human volunteers in Mali, the United Kingdom and the United States after showing very promising results in animal research. . (AP Photo/WHO/Mathilde Missioneiro) 

Swissmedic said the trial will be conducted among 120 volunteer participants with support from the U.N. World Health Organization. The experimental vaccine is to be initially administered on healthy volunteers who will be sent as medical staff to fight the Ebola epidemic in West Africa.

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