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Ebola: Suitcase kit detects virus in 15 minutes, as vaccine testing nears final stages

INTERNATIONAL BUSINESS TIMES  by                  Jan. 15, 2015

Researchers at DPZ, Germany, have developed a simple Ebola diagnostics kit that detects the virus in 15 minutes, without requiring any electricity, cold chain or lab equipment.

Infection researcher Dr Ahmed Abd El Wahed and the head of the Unit of Infection Models at the German Primate Center (DPZ), Dr med. vet. Christiane Stahl-Hennig, present the ebola suitcase laboratory Abd El Wahed invented.Karin Tilch, DPZ

The diagnostics-in-a-suitcase that comes equipped with all the required reagents is operated by an integrated solar panel and a power pack.

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Health 2 Leading Ebola Vaccines Appear Safe, Further Tests Starting

ASSOCIATED PRESS  by Maria Cheng                                                                          Jan. 9, 2015
LONDON --The World Health Organizationsays the two leading Ebola vaccines appear safe and will soon be tested in healthy volunteers in West Africa.

After an expert meeting this week, WHO said there is now enough information to conclude that the two most advanced Ebola vaccines ? one made by GlaxoSmithKline and the other licensed by Merck and NewLink ? have "an acceptable safety profile."

In a press briefing on Friday, Dr. Marie-Paule Kieny, who heads WHO's Ebola vaccine efforts, said "the cupboard (for Ebola vaccines) is filling up rapidly."

She said further trials in healthy people in West Africa, including health workers, are scheduled to start soon. Kieny added several other vaccines were being developed in the U.S., Russia and elsewhere.

Read complete story.
http://abcnews.go.com/Health/wireStory/leading-ebola-vaccines-safe-tests-starting-28107527

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IMF to provide new funds to help three main Ebola-hit nations

REUTERS   by James Harding Giahyue                                                  Jan. 8, 2015

The International Monetary Fund is preparing around $150 million in additional support to Liberia, Sierra Leone and Guinea, the countries at the heart of the Ebola epidemic, the Fund's representative in Liberia told Reuters on Thursday.

"In Guinea and Sierra Leone, existing Fund financial programs are being augmented to provide more resources to these countries. In Liberia, a one-off disbursement under the Fund's Rapid Credit Facility is being considered," Charles Amo-Yartey told Reuters in an email.

The money could be made available in the first quarter of this year and would add to $130 million disbursed by the Fund in September.

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http://www.reuters.com/article/2015/01/08/health-ebola-imf-idUSL6N0UN3RA20150108

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Geographic information helps provide public health intelligence at mass gatherings

MEDICALNEWS TODAY                                                            Jan. 6, 2015

Infectious diseases are one of the many health issues that worry the organizers of mass gatherings, such as the Hajj and the World Cup. Geographers' tools of the trade can help event organizers to better plan, monitor and respond timely to such eventualities. The ways in which geographers gather, analyze, and visualize information provide health officials with clearer pictures of the transport routes and environmental factors that may further the spread of viruses to and from the attendees' home countries.

In Chapter 3 of the new book Health, Science and Place: A New Model, geographer and biologist Dr. Amy Blatt explains how geographic information is used for disease surveillance at mass gatherings.
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http://www.medicalnewstoday.com/releases/287577.php?tw

Read excerpt from the book,chapter 3.

by Dr. Amy Blatt
http://link.springer.com/chapter/10.1007%2F978-3-319-12003-4_3

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What providers can learn from infectious disease outbreaks

FIERCEHEALTHCARE                 by                                                                Jan. 5. 2015

(Two items. Scroll down.)

With the Ebola crisis far from over as a new year begins, both this current threat to global health as well as past infectious disease outbreaks carry important lessons for critical care providers, according to an article in the American Journal of Critical Care.

Because new pathogens are so unpredictable, "outbreaks reinforce the importance of critical care knowledge, skill and teamwork in uncertain situations," wrote Cindy L. Munro, R.N., Ph.D., and Richard H. Savel, M.D, both editors of the AJCC. "The recent Ebola outbreak reminds us that hand-washing, personal protective equipment and pristine technique are essential."

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The Race for the Ebola Vaccine

THE DAILY BEAST  by Abby Haglage                                                                  Jan. 7, 2015

...Although a few smaller companies have become involved in the race for a vaccine, three major pharmaceutical makers are taking the lead—each pursuing a different vaccine. The trials are unprecedented for a variety of reasons, including the rapid timeline (trials of this nature generally take three to four years).

                                                      Steve Parsons-WPA Pool/Getty Images

Each individual race involves an unusual collaboration between researchers, manufacturers, and public-health entities. Together, the teams are working 24 hours a day for a product that promises much higher risk than it does profit.

Here’s what you need to know about the Ebola vaccine front-runners.

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http://www.thedailybeast.com/articles/2015/01/07/the-race-for-the-ebola-vaccine.html

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J&J, Bavarian Nordic start clinical tests in Ebola vaccine race

REUTERS     by Ben Hirschler                              Jan. 6, 2015
LONDON --Johnson & Johnson has started clinical trials of its experimental Ebola vaccine, which uses a booster from Denmark's Bavarian Nordic, making it the third such shot to enter human testing.

The initiation of the Phase I study in Britain, which had been expected about now, marks further progress in the race to develop a vaccine against a disease that has killed more than 8,000 people in West Africa since last year.

Two other experimental vaccines, one from GlaxoSmithKline and a rival from NewLink and Merck, are already in clinical development. However, the J&J vaccine offers a different approach, since it involves two separate injections.

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http://www.reuters.com/article/2015/01/06/us-health-ebola-vaccine-j-j-idUSKBN0KF0HH20150106

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Merck-NewLink Ebola vaccine trial resumes at lower dose: Geneva hospital

(Two stories. Scroll down.)

REUTERS                                                       Jan. 5, 2015

GENEVA --The clinical trial of an Ebola vaccine developed by Merck and NewLink resumed on Monday at a lower dose after a pause to assess complaints of joint pains in some volunteers, the University of Geneva hospital said.

The Geneva hospital announced on Dec. 11 that its vaccine trial had been suspended as a precautionary measure after four patients complained of joint pains. On Monday, the hospital said 10 of 59 volunteers who received the vaccine had felt pains in their joints "similar to rheumatism" after some two weeks, but these symptoms had disappeared rapidly without any treatment.

Swissmedic, the Swiss regulatory agency, and ethics and safety committees have approved the resumption of the trial at a lower dose, the hospital said in a statement.

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http://www.reuters.com/article/2015/01/05/us-health-ebola-vaccine-idUSKBN0KE0XP20150105
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Ebola survivors in west Africa to share stories via mobile app

REUTERS                                                            Jan. 4, 2015   

Ebola survivors in the three west African countries worst hit by the epidemic will share their stories through a mobile application to be launched on Monday, in a Unicef-backed campaign to inform and fight stigma around the disease.

...Although many people have survived the disease, they still face rejection and stigma from their communities, while the virus continues to spread due to lack of information and denial, according to the WHO and other health organisations.

The campaign, called #ISurvivedEbola, is funded by US philanthropist and co-founder of Microsoft Paul G Allen’s foundation which has committed $100m to fight the disease. Unicef, the UN children’s agency is collaborating in the project.

Survivors in Guinea, Sierra Leone and Liberia will be given smartphones and will document their stories and exchange tips on how to cope with it for a mobile app which will be available to the public, the backers said in a statement.

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FDA allows testing of Aethlon device in Ebola patients

REUTERS                                                        Jan. 2, 2015

SAN DIEGO- Calif. --Aethlon Medical Inc said the U.S. Food and Drug Administration had approved the testing in Ebola patients of its bio-filtration device, which was used against the deadly virus in a critically ill patient in Germany who later recovered.

The device, being developed as a broad-spectrum countermeasure against pandemic threats, filters viruses and toxins from the blood.

It is currently being tested in India for its ability to accelerate viral load depletion when used in combination with hepatitis C standard-of-care drug therapy.

Patients will be treated for six to eight hours daily with the device, called Aethlon's Hemopurifier, until the Ebola viral load drops below 1,000 copies/ml.

Read complete story.
http://www.reuters.com/article/2015/01/02/health-ebola-aethlon-med-idUSL3N0UH15720150102

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