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Outbreak of African Swine Fever Threatens to Spread from China to Other Asian Countries

           

There is no effective vaccine to protect swine from the disease.

FAO urges regional collaboration including stronger monitoring and preparedness measures

fao.org - August 28, 2018

The rapid onset of African Swine Fever (ASF) in China, and its detection in areas more than one thousand kilometres apart within the country, could mean the deadly pig virus may spread to other Asian countries anytime, the UN's Food and Agriculture Organization (FAO) warned today. 

There is no effective vaccine to protect swine from the disease. And, while the disease poses no direct threat to human health, outbreaks can be devastating with the most virulent forms lethal in 100 percent of infected animals.

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ALSO SEE RELATED ARTICLE HERE - 'It’s not if, it’s when': the deadly pig disease spreading around the world

 

 

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China Has Withheld Samples of a Dangerous Flu Virus

           

Health workers attending to an H7N9 avian flu patient in Wuhan, China, in 2017. CreditCreditAgence France-Presse -- Getty Images

CLICK HERE - WHO - Pandemic influenza preparedness Framework for the sharing of influenza viruses and access to vaccines and other benefits (68 page .PDF document)

Despite an international agreement, U.S. health authorities still have not received H7N9 avian flu specimens from their Chinese counterparts.

nytimes.com - by Emily Baumgaertner - August 27, 2018

For over a year, the Chinese government has withheld lab samples of a rapidly evolving influenza virus from the United States — specimens needed to develop vaccines and treatments, according to federal health officials.

Despite persistent requests from government officials and research institutions, China has not provided samples of the dangerous virus, a type of bird flu called H7N9. In the past, such exchanges have been mostly routine under rules established by the World Health Organization.

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Ticks on Migratory Birds Found to Carry Newly Discovered Hemorrhagic Fever Virus

           

Credit: Tove Hoffman

CLICK HERE - STUDY - CDC - EID - Alkhurma Hemorrhagic Fever Virus RNA in Hyalomma rufipes Ticks Infesting Migratory Birds, Europe and Asia Minor

uu.se - Press Release - June 1, 2018

In a new study, researchers at Uppsala University and other institutions have identified genetic material from the recently identified Alkhurma hemorrhagic fever virus in the tick species Hyalomma rufipes. The discovery was made after thousands of ticks were collected from migratory birds captured in the Mediterranean basin. The results indicate that birds could contribute to spreading the virus to new geographical areas.

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Beware 'Disease X': The Mystery Killer Keeping Scientists Awake at Night

CLICK HERE - WHO - R&D Blueprint - List of Blueprint priority diseases

telegraph.co.uk - by Alanna Shaikh - March 10, 2018

Over two days in early February, the World Health Organisation (WHO) convened an expert committee at its Geneva headquarters to consider the unthinkable.

The goal was to identify pathogens with the potential to spread and kill millions but for which there are currently no, or insufficient, countermeasures available . . . 

 . . . In addition to eight frightening but familiar diseases including Ebola, Zika, and Severe Acute Respiratory Syndrome (SARS), the list included a ninth global threat: Disease X.

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ALSO SEE RELATED ARTICLE HERE - Mysterious 'Disease X' Could Be The Next Deadly Global Epidemic, WHO Warns

 

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Chinese Scientists Find How Bats Carry Viruses Without Getting Sick

xinhuanet.com - Editor: Liu - February 23, 2018

CLICK HERE - Dampened STING-Dependent Interferon Activation in Bats

WASHINGTON, Feb. 22 (Xinhua) -- Chinese scientists have identified the secret of bats that harbor highly pathogenic viruses like Ebola, Marburg and SARS coronavirus but do not show clinical signs of disease.

In a paper published on Thursday in the journal Cell Host & Microbe, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, so bats can maintain just enough defense against illness without triggering a heightened immune reaction.

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BRIEF: The Virome Project Aims to Prepare Before the Next Pandemic

           

Ebola virus budding from surface of cells, from a scanning electron micrograph.  Image credits: NIAID

CLICK HERE - The Global Virome Project

insidescience.org - by Benjamin Plackett - February 22, 2018

 . . . In an article published in Science magazine today, Daszak and a group of like-minded scientists described a new initiative, called the Virome project, that would identify and catalogue hundreds of thousands of yet-to-be-discovered viruses found in wild animals.

The team estimates that there are about 1.6 million undiscovered virus types and that somewhere between 631,000-827,000 could potentially spill over into humans. The viruses are found mostly in wild mammals.

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China Confirms First Ever Human Case of H7N4 Bird Flu

           

China has confirmed first ever human case of H7N4 bird flu Photograph: Kin Cheung/AP

CLICK HERE - The Government of Hong Kong Special Administrative Region - Press Release

A 68-year-old patient from Jiangsu province, who has since recovered, developed symptoms on Christmas Day and was admitted to hospital

theguardian.com - by Tom Phillips - February 15, 2018

A woman from eastern China has been confirmed as the first ever human case of H7N4 bird flu, according to Chinese authorities . . .

 . . . The 68-year-old patient from Jiangsu province, who has since recovered, developed symptoms on 25 December, was admitted to hospital for treatment on 1 January and was released on 22 January. 

“She had contact with live poultry before the onset of symptoms,” Hong Kong’s centre for health protection (CHP) said in an alert on Wednesday evening. “According to a report from the Chinese centre for disease control and prevention, upon analysis, the genes of the virus were determined to be of avian origin.”

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The World Bank - Operational Framework for Strengthening Human, Animal and Environmental Public Health Systems at Their Interface

                                                 

documents.worldbank.org - 29 January 2018

Abstract

Public health systems have critical and clear relevance to the World Bank’s twin goals of poverty eradication and boosting shared prosperity. In particular, they are impacted by, and must respond to,significant threats at human-animal-environment interface. Most obvious are the diseases shared between humans and animals (“zoonotic” diseases), which comprise more than 60 percent of known human infectious pathogens; but also aspects of vector-borne disease, food and water safety and security, and antimicrobial resistance. Public health systems must therefore be resilient and prepared to face existing and future disease threats at the human-animal-environment interface. the Operational Framework provides a strong orientation to One Health to assist users in understanding and implementing it, from rationale to concrete guidance for its application. Six core chapters are included, supported by annexes diving deeper into operational tools and recent World Bank alignment with One Health topics, and a glossary that explains key terms, including interpretations specific to the Operational Framework.

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Bat Cave Solves Mystery of Deadly SARS Virus — and Suggests New Outbreak Could Occur

           

Researchers analysed strains of SARS virus circulating in horseshoe bats, such as this one (Rhinolophus sinicus), in a cave in Yunnan province, China.  Credit: Libiao Zhang/Guangdong Institute of Applied Biological Resource

Chinese scientists find all the genetic building blocks of SARS in a single population of horseshoe bats.

CLICK HERE - RESEARCH - Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

nature.com - by David Cyranoski - December 1, 2017

After a detective hunt across China, researchers chasing the origin of the deadly SARS virus have finally found their smoking gun. In a remote cave in Yunnan province, virologists have identified a single population of horseshoe bats that harbours virus strains with all the genetic building blocks of the one that jumped to humans in 2002, killing almost 800 people around the world. 

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Where Does the Ebola Virus Hide Between Outbreaks?

           

Photo by Steve Babuljak

ucsf.edu - by Samantha Ancona Esselmann, Samantha Hindle and Ben Mansky - October 24, 2017

Joe DeRisi, PhD, is a master detective of infectious diseases. No matter how obscure or complex, he says he’ll take on the challenge because “it could lead to new biology that we wouldn’t have discovered otherwise.”

That's precisely what happened when he stumbled on a clue to cracking the decades-long search for the place – or creature – where the Ebola virus hides between deadly outbreaks. . . .

 . . . In 2009, DeRisi began studying an incurable disease that was killing reptiles raised in captivity, a disease that caused strange neurological symptoms ranging from vomiting to uncontrollable contortions. They found the culprit – a previously undescribed arenavirus – and uncovered something surprising: the Arenavirus’s glycoprotein, a viral “access badge” to the secure insides of a cell, actually belonged to the Ebola virus.

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