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Hospital Records Are Adapting to Flag Ebola

A New Application Matches Patient’s Travel and Family History With Medical Symptoms

WALL STREET JOURNAL                         Nov. 3, 2014
By Melina Beck

A month ago, Massachusetts General Hospital in Boston had no way to flag in its electronic medical records if an incoming patient had been to West Africa and had symptoms suggesting Ebola.

Now it does. Five days after the first U.S. case was confirmed in Texas, the hospital deployed a new Ebola application made by QPID Health Inc. that automatically matches a patient’s travel and family history with medical symptoms. If Ebola is suspected, the application flashes a blinking “Q” to alert hospital personnel.

Dr. Garry Choy, who helped design Mass General’s QPID system. Dominick Reuter

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Researchers Study Ebola Link to Gene in Rare Disease

WALL STREET JOURNAL                             Nov 3, 2014

By Amy Dockser Marcus

In the search for answers about Ebola, researchers are starting to look at an unexpected group of people: parents of children who have the rare but fatal genetic disease Niemann-Pick Type C.

Blood and tissue samples from Hugh and Chris Hempel of Reno, Nev., whose children have a rare disease, may help in ongoing Ebola research. Hempel family

The intersection between research in Ebola and NPC disease was surprising, and came after two scientific papers were published in 2011 demonstrating that a protein made by the same gene related to NPC disease is essential for Ebola infection.

Ebola uses the so-called NPC1 protein made by the gene to get into the cell and replicate the virus.

Now, research suggests that the gene that causes NPC disease may also offer protection against Ebola.

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http://online.wsj.com/articles/researchers-study-ebola-link-to-gene-in-rare-disease-1414965218

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Can a U.S. military Ebola treatment center slow Ebola in one hard-hit city?

WASHINGTON POST                                Nov. 3, 2014
By Kevin Sieff

GANTA, LIBERIA  --
The U.S. is erecting a new Ebola treatment center, slated to be ­finished later this month and manned by newly imported doctors. Just the sight of American helicopters flying over Ganta, a city of about 50,000, has lifted hopes here.

...a modern treatment center won’t be enough to eliminate Ebola in a place where the outbreak ­appears to rise and fall every few weeks and where victims sometimes disappear into remote communities with the disease. The question is whether those victims can be persuaded to use the new facility once it is built, preventing the spread of the disease in some of the country’s most vulnerable ­areas.
http://www.washingtonpost.com/world/africa/can-a-us-military-ebola-treatment-center-slow-ebola-in-one-hard-hit-city/2014/11/01/afb7b058-60fd-11e4-9f3a-7e28799e0549_story.html

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The toll of a tragedy

An infographic of the toll of the Ebola outbreak.

Image: An infographic of the toll of the Ebola outbreak.

economist.com - October 31st 2014

The first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak.

(VIEW COMPLETE ARTICLE AND FULL SIZE INFOGRAPHIC)

 

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What We Don’t Know About Ebola

Overview of what still needs to be learned about the Ebola virus

Research studies have suggested at least three potential paths through which the Ebola virus can invade tissues. Credit Photograph by the C.D.C. via Getty Images

THE NEW YORKER                                      Nov. 1, 2014

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...there are still serious gaps in what we know about the biology of Ebola, and that ignorance inhibits us from preventing future outbreaks and reducing death rates that still exceed seventy per cent. We don’t know enough about the biology of Ebola to bring the outbreak under full control, or to neutralize the virus once the outbreak is contained. Between on-the-ground efforts and advances in science, we need a balanced approach.

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New York doctor with Ebola improves, nurse reunited with dog

REUTERS                                         Nov. 1, 2014
By Jill Serjeant

NEW YORK --A New York doctor with Ebola, who triggered a national debate over mandatory quarantines for health workers returning from West Africa, was upgraded to stable condition on Saturday after nine days of treatment.

Dr. Craig Spencer, 33, the only person in the United States currently being treated for Ebola, will remain in isolation, New York City's Bellevue Hospital said in a statement. He has improved to "stable" from "serious but stable...."

...Texas nurse Nina Pham, 26, who recovered from Ebola last week after treating a Liberian patient in a Dallas hospital, was reunited on Saturday with her dog, which had been quarantined for three weeks as a precaution.

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http://www.reuters.com/article/2014/11/01/us-health-ebola-usa-idUSKBN0II1SP20141101

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Scientists Try to Predict Number of US Ebola Cases

ASSOCIATED PRESS                                                                                NOV. 1, 2014
By MARTHA MENDOZA

STANFORD, Calif.--Top medical experts studying the spread of Ebola say the public should expect more cases to emerge in the United States by year's end as infected people arrive here from West Africa, including American doctors and nursesreturning from the hot zone and people fleeing from the deadly disease.

But how many cases?

No one knows for sure how many infections will emerge in the U.S. or anywhere else, but scientists have made educated guesses based on data models that weigh hundreds of variables, including daily new infections in West Africa, airline traffic worldwide and transmission possibilities.

This week, several top infectious disease experts ran simulations for The Associated Press that predicted as few as one or two additional infections by the end of 2014 to a worst-case scenario of 130.

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http://abcnews.go.com/Health/wireStory/scientists-predict-number-us-ebola-cases-26621993

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Analysis: Alarmed by Ebola, Public Isn’t Calmed by ‘Experts Say’

NEW YORK TIMES                        NOV. 1, 2014
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When public health leaders and government officials make the case against isolating more people returning from the Ebolahot zones in West Africa, or against imposing more travel restrictions from that region, time and again they cite science and experts. It isn’t working very well.

Many support the efforts of Gov. Paul R. LePage of Maine to isolate a nurse who treated Ebola patients in West Africa. Credit Craig Dilger for The New York Times

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WHO Updates Guidelines on Ebola Protective Gear

A U.S. doctor in a protective suit in Liberia adjust that of a colleague before entering an Ebola treatment unit in Monrovia in this photo released Sept. 16, 2014.

These updated guidelines aim to clarify and standardize safe and effective PPE options to protect health care workers and patients, as well as provide information for procurement of PPE stock in the current Ebola outbreak. The guidelines are based on a review of evidence of PPE use during care of suspected and confirmed Ebola virus disease patients.

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http://www.who.int/mediacentre/news/releases/2014/ebola-ppe-guidelines/en/

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Better Staffing Seen as Crucial to Ebola Treatment in Africa

NEW YORK TIMES                               Nov. 1, 2014

By Denise Grady

...The stark difference in the care available in West Africa and the United States is reflected in the outcomes...., In West Africa, 70 percent of people with Ebola are dying, while seven of the first eight Ebola patients treated in the United States have walked out of the hospital in good health. Only one died: Thomas Eric Duncan, a Liberian, whose treatment was delayed when a Dallas hospital initially misdiagnosed his illness.

  

Dr. Rick Sacra, a missionary who was infected with Ebola in Liberia and was successfully treated at the Nebraska Medical Center. Credit Brendan Sullivan/Omaha World-Herald, via Associated Press

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