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Cheap Paper Test to Screen Patients for Ebola, Yellow Fever, Dengue

MEDGADGET                                                                                   Aug. 20, 2015

BOSTON --At the 250th National Meeting & Exposition of the American Chemical Society this week, researchers from MIT, Harvard Med School, and the FDA are showing off a new field test that can quickly screen people for Ebola, yellow fever, and dengue. While the researchers don’t claim their technique to be as accurate as PCR and ELISA, it is nevertheless an excellent tool in poor areas of the world where these diseases tend to thrive.

The test doesn’t require any water or electricity nor any complicated and expensive equipment. It works similar to pregnancy tests, providing a color readout that signals whether a disease is detected that is easily readable by just about anyone.

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Ebola: What Happened

COUNCIL ON FOREIGN RELATIONS  BY John Campbell
(Scroll down for Laurie Garett's essay "Ebola's Lessons.")

With a rapidly growing and urbanizing population, persistent poverty, and weak governance, Sub-Saharan Africa is likely to be the source of new epidemics that potentially could spread around the world. Understanding the disastrous response of African governments, international institutions, and donor governments to the Ebola epidemic is essential if history is not to be repeated yet again. That makes Laurie Garrett’s essay, “Ebola’s Lessons,” in the September/October 2015 issue of Foreign Affairs, essential reading.

The Ebola virus treatment center where four people are currently being treated is seen in Paynesville, Liberia, July 16, 2015. (Courtesy Reuters/James Giahyue)

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The Use of Intraosseous Fluid Resuscitation in a Pediatric Patient with Ebola Virus Disease

jem-journal.com - by Michael L. Paterson and Charles W. Callahan - August 14, 2015

 
Abstract
 
Background

Vomiting, diarrhea, and severe dehydration are common manifestations of Ebola virus disease (EVD), leading to its high mortality. Mortality is especially high in patients older than 45 years, younger than 5 years, and in pregnant women and their fetuses. The majority of patients with EVD are not able to tolerate the quantities of oral hydration solutions necessary to rehydrate properly. Although some have speculated that IV and intraosseous lines are not practical in the austere, resource-constrained settings of an Ebola treatment unit during an epidemic, it is necessary to provide parenteral fluids and electrolyte replacements to significantly decrease mortality. Due to the inability to spend long periods of time working in hot environments wearing personal protective equipment, it is necessary to maximize the use of rapidly obtainable and safe parenteral access.

Case Report
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Some Ebola Survivors Still Suffer—And Doctors Don’t Know Why

SCIENCE    by  Katie  M. Palmer                      Aug. 15, 2015

For the communities in Guinea, Sierra Leone, and Liberia where Ebola took the greatest toll last year, the worst is over. After claiming 11,000 lives, the fatal virus has finally begun to retreat. Numbers of new Ebola cases are dwindling. But for some of the survivors—the 50 percent or so of the infected who pull through—Ebola’s effects still linger.

                            Ebola survivor Fayiah, 11, sits with her relatives in Monrovia, Liberia. Jerome Delay/AP

For the communities in Guinea, Sierra Leone, and Liberia where Ebola took the greatest toll last year, the worst is over. After claiming 11,000 lives, the fatal virus has finally begun to retreat. Numbers of new Ebola cases are dwindling. But for some of the survivors—the 50 percent or so of the infected who pull through—Ebola’s effects still linger.

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Using Public-Private Partnerships to Combat Ebola Globally

           

The Completed Containerized Biocontainment Systems Units at Dobbins Air Force Base, in Marietta, Georgia

blogs.state.gov - by Andrew O'Brien - August 13, 2015

In treating Ebola internationally, U.S. government personnel, doctors, nurses, aid workers, and other global health professionals are often put in direct contact with Ebola, and unfortunately some contract the virus themselves. Yet with limited resources, the U.S. Department of State needed more capacity to safely transport these Ebola patients to treatment facilities. Additionally, availability of medevac is important to getting doctors and epidemiologists from all over the world to volunteer to join the Ebola response.

By partnering with the Paul G. Allen Family Fund we were able to confront this challenge head on. Two containerized medevac biocontainment systems were funded by a $5 million grant by the Paul G. Allen Family Fund and the units were unveiled on August 11th at an event recognizing the partnership. MRIGlobal, a leading research institute, built the units, which are fully equipped to transport four patients, contain a broader array of dangerous pathogens, and fly aboard both military and civilian aircraft to multiple destinations in a single mission.

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How The Department of Defense Helped Confront Ebola

GEORGETOWN PUBLIC POICY REVIEW by Col.Russell E. Coleman   Aug. 12, 2015
WASHNGTON -- More than 10,000 people have died of Ebola virus disease (EVD) since the outbreak in West Africa began in December 2013. An epidemic of this magnitude, whether naturally occurring or caused by a biowarfare agent, could compromise both the U.S. health care system and the U.S. military’s ability to defend this country and its allies.


This possibility, long recognized by the Department of Defense (DoD), drives the department’s development of medical countermeasures. The response to the current Ebola outbreak demonstrates how DoD prepares for a medical threat without knowing (1) where it will happen, (2) when it might happen, (3) what the disease will be, and (4) what local resources will be immediately available.

Read complete article.
http://gppreview.com/2015/08/12/how-the-department-of-defense-helped-confront-ebola/

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Handwashing in W.African schools protects children, families from Ebola: UN

REUTERS by Monica MacSwan                                                                     Aug. 12, 2015

LONDON -- Handwashing and giving out soap in schools in Guinea, Liberia and Sierra Leone have helped to keep classrooms Ebola-free this year but schools need to remain vigilant after the summer holidays, the U.N. children's agency said on Wednesday.

UNICEF said there had been no reported cases of students or teachers contracting Ebola at a school this year in the three worst-hit countries in West Africa, where the virus has killed nearly 11,300 people since the outbreak began in late 2013.

In Liberia, where there have been as many as 4,800 deaths, two schools were decontaminated as a precaution after one student died in June and another became infected in July.

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How Will We Ensure the New Ebola Vaccine Reaches Those Most in Need?

HUFFINGTON POST  by Director of UNDP’s HIV, Health and Development Group, Bureau of Policy and Programme Support      Aug. 10, 2015                                                                 

 We have reasons to be optimistic about the news of a new tool in the fight against Ebola. As in the fight against HIV, science and solidarity have come together to save lives. The phase III trials on efficacy of the VSV-ZEBOV vaccine have yielded an impressive result in a relatively short time -- 100 percent effectiveness in those receiving the vaccine.

While scientists still need to figure out how long the protective effect of the vaccine lasts, and how effective it will be among the general population and with different strains of the virus, without a doubt this is an important tool for the protection of health and community workers and possibly the wider community. This will certainly help in the on-going efforts to achieve the target of zero new Ebola cases and in overall recovery efforts.

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