Conakry

One of the most devastating consequences of the Ebola outbreak will be its impact on maternal health.

NATURE  by Erika Check Hayden                                                                                       March 5, 2015
...Ebola is having tremendous knock-on effects for maternal health in Liberia, Guinea and Sierra Leone. Pregnancy seems to make women uniquely vulnerable to the effects of the disease, and babies born to infected women have not been known to survive.

Uninfected but affected: women line up for perinatal care at a Marie Stopes centre in Sierra Leone. Marie Stopes, Sierra Leone, supported by DFID/UKAID

Compounding these individual tragedies, the blood and abundant bodily fluid that accompanies delivery or miscarriage pose enormous risk of infection to health workers. As a result, many refuse to treat patients who are pregnant for fear that they will become infected.

LIVE SCIENCE  by Rahael Retner                             March 5, 2015

Texas nurse Nina Pham, who was infected with Ebola, says she has had ongoing health problems since being cured of the disease, and experts say this is not uncommon for Ebola survivors.

The long-term effects of Ebola have not been well studied, and doctors will likely learn a lot more about the disease's aftermath from the most recent outbreak in West Africa, the largest in history, said Dr. Jesse Goodman, an infectious-disease expert and a professor of medicine at Georgetown University Medical Center in Washington, D.C.

 But it is clear that Ebola survivors can experience health problems that remain with them temporarily as a result of their battle with the disease, Goodman said....

 These symptoms may result, in part, from the body's release of certain immune-system chemicals called cytokines. These chemicals fight the disease but make people feel sick. Dehydration, low blood pressure and nutrition problems that people experience during an Ebola infection can also injure a person's muscles or other tissues, Goodman said.

REUTERS by Kate Kelland and Tom Miles                      March 5, 2015

LONDON/GENEVA --Final stage trials of an Ebola vaccine being developed by Merck and NewLink Genetics will begin in Guinea on March 7, the World Health Organization said on Thursday.

Signaling global health authorities' determination to see through trials despite a sharp drop in cases in the West Africa epidemic, the WHO said a second shot, developed by GlaxoSmithKline will be tested "in a sequential study, as supply becomes available".

All three worst-hit countries - Guinea, Liberia and Sierra Leone - aim to conduct final-stage trials of vaccines, and Liberia is already testing the GlaxoSmithKline and Merck-NewLink shots, while Sierra Leone is expected to announce plans soon.

But recent steep declines in new Ebola cases will make it far harder to prove whether experimental vaccines work, as the vaccine's effect will be difficult to establish.

The WHO, however, said it was committed to pushing ahead.

Read complete story.
http://www.reuters.com/article/2015/03/05/us-health-ebola-vaccine-idUSKBN0M10ZD20150305

Description of key Ebola areas---MSF

MSF                                                        March 3, 2015

The Ebola outbreak in West Africa continues, albeit with decreasing intensity. The virus has infected more than 23,700 people across the region since the outbreak was declared 11 months ago. While the number of new patients in Liberia is declining, numbers are still fluctuating in both Guinea and Sierra Leone. A total of 99 new confirmed cases were reported across the three worst affected countries during the week up to 22 February 2015.

The unpredictable nature of the epidemic means that teams from Médecins Sans Frontières/Doctors Without Borders (MSF) are maintaining a flexible approach and continuing to respond where the needs are greatest in Guinea, Liberia and Sierra Leone.

See country-by-country analysis and complete story.

http://www.msf.org/article/ebola-epidemic-not-over-%E2%80%93-key-areas-still-need-be-tackled