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An experimental Ebola vaccine looks promising in a human trial

Vaccine  was made by introducing an Ebola gene in a chimpanzee cold virus

THE VERGE    by Arielle Duhaime-Ross                                                             Jan. 28, 2015

An Ebola vaccine produced using a chimpanzee common cold virus appears to be safe to use on humans, according to a study published today in the New England Journal of Medicine. Three different doses of vaccine were tested on healthy humans in the UK, and it was well-tolerated; it triggered high levels of antibody formation without also triggering serious side effects. But until the vaccine is tested in an area where an Ebola risk actually exists, it’s efficacy against the disease will remain a mystery.

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http://www.theverge.com/2015/1/28/7930947/ebola-vaccine-human-trials-results

A Monovalent Chimpanzee Adenovirus Ebola Vaccine — Preliminary Report

 New England Journal of Medicine

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WHO - Resolution - Executive Board Special Session on Ebola

                                        

CLICK HERE - WHO - Resolution - Ebola: Ending the current outbreak, strengthening global preparedness and ensuring WHO capacity to prepare for and respond to future large-scale outbreaks and emergencies with health consequences (11 page .PDF report)

CLICK HERE - Executive Board Special Session on Ebola - Additional supporting documentation

chathamhouse.org - by Dr. Charles Clift - January 27, 2015

The executive board of the World Health Organization (WHO) agreed a comprehensive resolution on its response to the Ebola crisis in a special session on 25 January. After the WHO was widely criticized for its perceived inadequacies in dealing with the Ebola outbreak in West Africa, the resolution asks for a transformation in the way the organization works in health emergencies. The WHO admits there is substance in these criticisms – with Margaret Chan, WHO’s director-general (DG), acknowledging shortcomings in WHO’s ‘administrative, managerial and technical infrastructures’.

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How Ebola Found Fertile Ground in ​Sierra Leone's Chaotic Capital

 

Kroo Bay in Freetown, Sierra Leone's capital, became an Ebola hot spot in December. In one of the city's most densely populated areas, residents had a difficult time avoiding contact with people potentially infected with Ebola.

NATIONAL GEOGRAPHIC    by Amy Maxman    Photos by Pete Muller                                                       Jan. 27, 2015
....A close examination of what made Freetown so vulnerable to the outbreak offers critical lessons for the future in fighting Ebola or another major calamity. 

Like many developing world cities, Freetown—population 941,000, the largest city in Sierra Leone—lacks the infrastructure to support its impoverished populace, making it prone to tragedy, whether through pestilence, violence, or natural disaster. Despite its congestion, Freetown continues to attract people who come in search of work, school, and the mere promise of electricity. It's no coincidence that typhoid and cholera regularly plague Freetown and that Sierra Leone's civil war climaxed in the city with horrific bloodshed.

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African Union vows Ebola fund as Oxfam calls for 'Marshall Plan'

AFP                                                                                                             Jan. 28, 2015
Addis Ababa - The African Union plans to launch an Ebola fund and disease control centre, officials said Wednesday, as aid agency Oxfam warned leaders needed to keep their promises to boost healthcare systems on the continent.

 Oxfam called for a "massive post-Ebola Marshall Plan", referring to the United States aid package to rebuild Europe after World War II....

AU Commissioner for Social Affairs Mustapha Sidiki Kaloko on Wednesday said an African Centre for Disease Control and Prevention would be set up by mid-2015.

"It is a reality, it is going to happen," Kaloko said, with the first phase concentrating on setting up "an early warning system" for the detection of epidemics. "We should be ready the next time. We shouldn't be caught unprepared."

However, its exact location remains undecided.

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http://news.yahoo.com/african-union-pledges-ebola-fund-oxfam-calls-marshall-145446661.html;_ylt=AwrBEiFLBMlUpSsAOxfQtDMD

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Lessons from Ebola: Toward a Post-2015 Strategy for Pandemic Response


Broadcast live streaming video on Ustream

This event has concluded. View the replay above.

worldbank.org - Date: January 27th 2015 - Location: Georgetown University & Online Time: 4:00 p.m. - 5:00 p.m. ET (21:00 - 22:00 GMT)

Jim Yong Kim, President of the World Bank Group, will deliver Georgetown’s inaugural Global Futures lecture.

The lecture, “Lessons from Ebola: A post-2015 strategy for pandemic response,” will kick off a semester-long conversation about the “Global Future of Development” at Georgetown as part of the university’s new Global Futures Initiative.

His talk on Jan. 27 will connect ongoing efforts to stop the spread of infection in West Africa with longer-term efforts to improve public health systems that support economic and social development in countries vulnerable to future pandemics.

http://live.worldbank.org/lessons-from-ebola-post-2015

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After Ebola, World Bank Chief Proposes Global Insurance Program For Future Outbreaks

INTERNATIONAL BUSINESS TIMES  by       Jan. 27, 2015

World Bank Group President Jim Yong Kim is proposing emerging nations, developed countries and global aid organizations participate in a kind of insurance system to help pay for health crises like West Africa's Ebola outbreak. “We need to prepare for future pandemics that could become far more deadly and infectious than we we have seen so far with Ebola,” Kim told an audience at Georgetown University on Tuesday. “We must learn the lessons from the Ebola outbreak because there is no doubt we will be faced with other pandemics in the years to come.”

 ...according to Kim, the recent outbreak could be just the beginning. And world leaders need a plan.  

He said World Bank officials informally discussed the possibility of a “pandemic response facility” with the World Health Organization, United Nations and other international actors last week at the World Economic Forum in Davos, Switzerland.

“This could work like insurance policies that people understand, like fire insurance,” Kim said. “The more that you are prepared for a fire, such as having several smoke detectors in your home, the lower the premium you pay.”

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Scientists ask if Ebola immunizes as well as kills

LONDON/DAKAR--A recent sharp drop in new Ebola infections in West Africa is prompting scientists to wonder whether the virus may be silently immunizing some people at the same time as brutally killing their neighbors.

A health worker disinfects a road in the Paynesville neighborhood of Monrovia, Liberia, January 21, 2015. Credit: Reuters/James Giahyue

So-called "asymptomatic" Ebola cases - in which someone is exposed to the virus, develops antibodies, but doesn't get sick or suffer symptoms - are hotly disputed among scientists, with some saying their existence is little more than a pipe dream.

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Post-Ebola plan needed to avert 'double disaster' in West Africa: Oxfam

REUTERS   by Magdalena Mis                                                                             Jan. 26, 2015

LONDON -- The three West African countries worst hit by Ebola risk a "double disaster" unless a multi-million dollar plan is put in place to help their economies recover, Oxfam said on Tuesday.

In Liberia, Guinea and Sierra Leone people were struggling to make ends meet having seen their incomes plummet, the aid agency said.

"The world was late in waking up to the Ebola crisis, there can be no excuses for not helping to put these economies and lives back together," Mark Goldring, Oxfam's chief executive, said during a visit to Liberia.

He said a post-Ebola "Marshall Plan" should address three areas of urgent need: cash for families affected by the crisis, investment in jobs and support for basic services.

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http://www.reuters.com/article/2015/01/27/us-health-ebola-oxfam-idUSKBN0L000520150127

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After Ebola: Why Rural Development Matters in a Time of Crisis

COMMENTARY:  HUFFINGTON POST  by President, International Fund for Agricultural Development (IFAD)                                                                                                                                 Jan. 26, 2015

....Now we must begin to look at what happens to the affected communities after Ebola. A food crisis seems increasingly likely to follow in the wake of the epidemic, which has devastated small-scale farmers. Without investment in their long-term development, farming households - and West Africa's future food security - will remain at risk.

Even before the outbreak, the World Food Programme estimated that some 1.7 million people in the region faced food insecurity - defined as a lack of reliable access to sufficient quantities of affordable, nutritious food. As a direct result of Ebola, it is expected that an additional 750,000 to 1.4 million people will become food-insecure by March.

In fact, Ebola has already affected the food supply. Farmers have stayed away from their fields due to illness, fears of infection and quarantines ordered by the authorities - or simply because there is no one left to tend the land....

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Studies detail Ebola spread, response steps

Four new studies shed new light on Ebola transmission and countermeasures.

CENTER FOR EFFECTIVE FOR RESEARCH AND POLICY  by Lisa Schnirring                                        Jan. 23, 2015

French and Guinean researchers  noted how chains of transmission helped Ebola spread in Conakry, Guinea, the first of the region's capital cities to be hit by the virus, and US officials released three detailed reports on outbreak response.

The Conakry team looked at seven transmission chains that occurred in the area from March to August 2014. They reported their findings in The Lancet Infectious Diseases.

In the first of three reports Friday in Morbidity and Mortality Weekly Report (MMWR), extra flight contact tracing measures undertaken after a Texas nurse took two flights shortly before getting sick with Ebola in October identified 268 people from nine states, none of whom got sick with the virus

In the second report, CDC estimates on the impact of Ebola treatment units (ETUs) and community care centers (CCCs) in Liberia predict that the interventions prevented thousands of new infections and that the interventions when used together were likely had a bigger impact than either alone.

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