Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy

Impt CDC study shows rate of microcephaly related to Zika similar among babies born in US to est rate in Brazil. https://t.co/cdSLRliPuo

— Dr. Tom Frieden (@DrFriedenCDC) December 15, 2016

jamanetwork.com - December 13, 2016 - doi:10.1001/jama.2016.19006

In this report based on preliminary data for pregnant women in the USZPR with laboratory evidence of possible Zika virus infection, 6% overall had a fetus or infant with evidence of a Zika-related birth defect, and among women with timing of possible Zika infection exclusively during the first trimester, 11% had a fetus or infant with a birth defect. The birth defects primarily involved included microcephaly with brain abnormalities, such as intracranial calcifications. Preliminary estimates from the USZPR were within the range of 1% to 13% risk of microcephaly following first-trimester maternal Zika virus infection modeled on the outbreak in Bahia, Brazil, lending support to the credibility of these estimates.

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