Infection of developing human brain with the Zika virus (green) highlights susceptibility of radial glial cells during fetal development. Image by Elizabeth Di Lullo
CLICK HERE - STUDY - PNAS - Zika virus cell tropism in the developing human brain and inhibition by azithromycin
ucsf.edu - by Laura Kurtzman - November 29, 2016
Working in the lab, UC San Francisco researchers have identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin, a common antibiotic regarded as safe for use during pregnancy, can prevent the virus from infecting these cells . . .
. . . In the new study, published online Nov. 29, 2016, in the Proceedings of the National Academy of Sciences (PNAS), the UCSF researchers determined that the Zika virus preferentially infects brain cells with an abundance of a protein called AXL, which spans the outer cell membrane of several cell types and serves as a gateway for the invading virus . . .