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Another American Doctor Infected With Ebola in Liberia

       

Missionary Doctor Being Treated in Monrovia Hospital

wsj.com - by Betsy McKay - simusa.org - September 2, 2014

A third American missionary has been infected with Ebola while working in Liberia and is being treated in an isolation unit in the Monrovia hospital where he works.

The man, a doctor, was treating obstetrics patients, not Ebola patients. . .

. . . It isn't known how the doctor was infected, SIM USA said in a statement Tuesday.

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CLICK HERE - STATEMENT from SIM - SIM Missionary Doctor in Liberia Tests Positive for Ebola

 

MSF - Response to the World Health Organization's Ebola Road Map

         

An MSF staff member at the Ebola treatment center in Monrovia, Liberia.  Caroline Van Nespen/MSF

doctorswithoutborders.org - August 28, 2014

Statement from MSF Director of Operations Brice de le Vingne.

“The WHO road map is welcome, but it should not give a false sense of hope. A plan needs to be acted upon. Huge questions remain about who will implement the elements in the plan. Who has the correct training for the variety of tasks that are detailed? How long will it take to train organizations to set up and run an Ebola management center? How long before any new centers become operational? Who will undertake the vitally important health education, contact tracing, and safe burials in the affected communities?

WHO - Ebola Response Roadmap

who.int

Publication details

Number of pages: 27
Publication date: August 2014
Languages: English

 

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Overview

WHO issued this roadmap for scaled-up response to the Ebola outbreak. The goal is to stop Ebola transmission in affected countries within 6-9 months and prevent international spread.

The roadmap will assist governments and partners in the revision and resourcing of country-specific operational plans for Ebola response, and the coordination of international support for their full implementation. The objectives are:

Experimental Ebola Drug Halts Virus in Monkeys Five Days After They Were Infected

CLICK HERE - RESEARCH - Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

washingtonpost.com - by Lenny Bernstein - August 29, 2014

The experimental drug pressed into emergency use in the West African Ebola epidemic cured a group of 18 monkeys of the deadly disease, including some who didn't receive the treatment until five days after they were injected with the virus, researchers reported Friday.

The finding, published online in the journal Nature, raises new hope for use of the cocktail of monoclonal antibodies, called ZMapp, against Ebola, which has no known cure or vaccine. . .

. . . "The highlight of these experimental results is undoubtedly ZMapp, which was able to reverse severe [Ebola] disease...leading to full recovery of all treated [non-human primates]" within 28 days after they were infected, the researchers wrote.

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Doctors and Nurses Risk Everything to Fight Ebola in West Africa

        

Craig Kenzie, Junko Otaki, and Luca Zaliani are among the 57 international health care workers assisting with Ebola treatment at a Médecins Sans Frontières facility in Kailahun, Sierra Leone.  Photographs by Samuel Aranda

Foreign and local caregivers are essential to stopping the virus’s deadly spread.

nationalgeographic.com - by Karen Weintraub - August 29, 2014

In two Land Rovers, one fitted out as an ambulance, a small team of humanitarian workers last week headed deep into Sierra Leone's jungle. After hours on deeply rutted paths that could barely be called roads, they stopped at a village that had seen ten reported cases of Ebola.

With the consent of the village chief, the team fanned out across the community, asking at each hut if anyone was feeling ill or had made contact with the earlier patients.

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US to Test Ebola Vaccine in Humans Amid Growing Outbreak in West Africa

      

An undated photo from National Institute of Allergy and Infectious Diseases and GlaxoSmithKline shows a vaccine candidate that will be used in the upcoming human trials.  NIAID/GSK/AP Photo

abcnews.go.com - by Katie Moisse - August 28, 2014

U.S. scientists will begin testing an Ebola vaccine in humans next week, health officials announced today. But it could take 11 months to learn whether the vaccine is safe as the virus’ toll in West Africa continues to rise. . .

. . . The experimental vaccine, co-developed by the National Institutes of Health and GlaxoSmithKline, “performed extremely well in protecting nonhuman primates from Ebola infection,” Dr. Anthony Fauci, director of the NIH’s infectious disease branch, said.

Ebola Virus Mutating Rapidly as it Spreads

Outbreak likely originated with a single animal-to-human transmission.

nature.com - Erika Check Hayden - August 28, 2014

Augustine Goba and his colleagues have now decoded the genetic sequences of 99 Ebola viruses collected from 78 patients during the first 24 days of the epidemic in Sierra Leone. The work, published online in Science, could help to inform the design of diagnostics, therapeutics and vaccines, says structural biologist Erica Ollmann Saphire of The Scripps Research Institute in La Jolla, California. “This paper is terrific,” she adds.

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Ebola Causing Huge Damage to West Africa Economies: Development Bank

         

Health workers wearing protective clothing prepare to carry an abandoned dead body presenting with Ebola symptoms at Duwala market in Monrovia August 17, 2014.  Credit: Reuters/2Tango

reuters.com - By Josephus Olu-Mammah and Umaru Fofana - August 27, 2014

(Reuters) - The worst ever Ebola outbreak is causing enormous damage to West African economies as foreign businessmen quit the region, the African Development Bank said, while a leading medical charity branded the international response "entirely inadequate."

As transport companies suspend services, cutting off the region, governments and economists have warned that the epidemic could crush the fragile economic gains made in Sierra Leone and Liberia following a decade of civil war in the 1990s. . .

. . . Air France, the French network of Air France-KLM said on Wednesday it had suspended flights to Sierra Leone after advice from the French government.

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Researchers Unlock Clues to How Ebola Disarms Immune System

cell.com - medicinenet.com - nlm.nih.gov - theramatch.com

WEDNESDAY, Aug. 13, 2014 (HealthDay News) -- Researchers say they've discovered how the deadly Ebola virus disables the immune system. They hope the findings will prove valuable in efforts to find treatments for the disease taking hundreds of lives in Africa. . .

. . . American researchers found that the Ebola protein VP24 disrupts a cell's natural immune response. They said this action is an important first step on Ebola's path to causing fatal disease, according to the study published Aug. 13 in the journal Cell Host & Microbe.

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CLICK HERE - STUDY - Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

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