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Zimbabwe - Mystery Disease Puzzles Doctors - Close to 50 People Admitted, 15 Cattle Dead

thezimbabwedaily.com - by Fairness Moyana - 21 May 2017

CLOSE to 50 people from Change, Dinde and Nekabandama in Hwange District, Matabeleland North have since the beginning of the month been hospitalised at Lukosi Hospital and surrounding health institutions complaining of severe pain which causes paralysis of the backbone, lower and upper body rendering patients immobile.

However, although no deaths have been reported in the area, health officials said they are failing to detect what the disease was or its causes after all patients tested negative for malaria which they were initially suspecting. Apart from the mystery of the disease, local people are now suspecting that there could be some poisonous plant or water source, as during the same time at least 15 cattle died under mysterious circumstances.

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POLIOMYELITIS UPDATE (06): SYRIA (DEIR AL ZOUR), CIRCULATING VACCINE DERIVED POLIOVIRUS SUSPECTED

promedmail.org - 12 May 2017

The current information is that there is a cluster of 23 AFP [acute flaccid paralysis] cases in Miadin district, with one of the specimens having a possible vaccine derived poliovirus (VDPV). Samples were sent to Atlanta for further testing.

A concern is that the VDPV is a cVDPV [circulating vaccine derived poliovirus] which is now considered to be just like a wild polio. (The virus is a type 2 virus).

The investigation will reveal the status of this case and the hope is that it will be ambiguous or perhaps in an immune deficient individual.

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CLICK HERE - ProMED mail - Updates

ALSO SEE RELATED ARTICLE WITHIN THE LINK BELOW . . .

CLICK HERE - Suspected polio cases found in Islamic State-controlled area of eastern Syria

 

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Hospitals On The Brink As Cholera Kills 184 In Yemen’s Capital In Mere Days

submitted by Alison Thompson

           

More than half of the health facilities in Yemen are closed or partially functioning due to severe shortages in medicines, infrastructure, equipment and staff.  AFP VIA GETTY IMAGES

The outbreak in Sanaa is the second in less than a year in the war-torn country.

huffingtonpost.com - by Rowaida Abdelaziz - May 16, 2017

 . . . At least 184 Yemenis have died of cholera just this weekend in the capital, which Houthi rebels have controlled for the past three years. On Sunday, the city declared a state of emergency and called for international help to deal with the crisis. Yemen’s health ministry, run by Houthi rebels, said on its news agency Saba that the outbreak was “unprecedented” and had become impossible “to contain.” There have also been cases of the disease have been reported in other major cities including Hodeidah, Taiz and Aden.

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Chasing Cures for Deadly Scourges, and Getting in Our Own Way

nytimes.com - RETRO REPORT - by Clyde Haberman - May 14, 2017

What do the C.I.A. and Nigerian imams have to do with the fight to end polio? Retro Report examines how the worlds of politics and public health can collide. By RETRO REPORT on May 14, 2017.

https://www.nytimes.com/2017/05/14/us/retro-report-disease-eradication.html

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New Zika Virus Inhibitor Identified

CLICK HERE - RESEARCH - Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

business-standard.com - ANI - May 17, 2017

A new research has brought a drug to treat Zika infections closer to reality.

The team led by Alexey Terskikh and Alex Strongin from Sanford Burnham Prebys Medical Discovery Institute (SBP) discovered a compound that prevents the virus from spreading.

"We identified a small molecule that inhibits the Zika virus protease, and show that it blocks viral propagation in human cells and in mice," Terskikh said. "Anti-Zika drugs are desperately needed. The fact that the compound seems to work in vivo is really promising, so we plan to use it as a starting point to make an even more potent and effective drug."

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US May Be Severely Underestimating Zika's Potential Impact; Costs Could Be in the Billions

Deadly carriers of disease: Aedes aegypti mosquitoes.  Paulo Whitaker | Reuters

Gulf Coast region is vulnerable to Zika attacks

Congress may not appreciate full extent of potential damage

Conservative calculations suggest full impact could exceed $2 billion

CLICK HERE - PLOS - The potential economic burden of Zika in the continental United States

cnbc.com - by Robert Ferris - May 11, 2017

The Zika virus stands to cost the United States billions of dollars, even if few people are infected.

Researchers from several American institutions have calculated that the "virus from Hell" could result in total costs ranging from $183 million to over $1.2 billion, depending on infection rates in several at-risk states in the South.

The researchers warn that infection rates could engender costs that exceed the amounts of money the U.S. government may give for prevention and treatment, if the recent debates over funding are any indication.

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Zika Testing Recommendations Changed for Pregnant Women

           

A nurse practitioner gives a pregnant woman insecticide and information about Zika at a Miami clinic last summer.  LYNNE SLADKY/AP

CLICK HERE - CDC - Health Alert Network (HAN) - Prolonged IgM Antibody Response in People Infected with Zika Virus: Implications for Interpreting Serologic Testing Results for Pregnant Women

statnews.com - by Helen Branswell - May 5, 2017

 . . . Testing for Zika infection is becoming more difficult, making it harder for doctors to advise pregnant women about the chances their child might have a Zika-related birth defect, the Centers for Disease Control and Prevention revealed in a health advisory issued Friday.

The CDC is now suggesting that women thinking of getting pregnant, and who may be exposed to the Zika virus through travel or because of where they live, should consider having their blood tested for Zika antibodies before they get pregnant. Having a baseline reading would help to interpret Zika tests done during a later pregnancy.

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Here’s the Ideal Temp for Mosquito-Borne Diseases

           

(Credit: budak/Flickr)

CLICK HERE - PLOS - Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models

futurity.org - Stanford University - May 5, 2017

New research shows how rising temperatures might influence mosquito behavior and disease risk around the world. The researchers also calibrated their model with field data on human infections of mosquito-borne diseases.

Scientists have known for some time that climate change has caused the extension of mosquito season beyond the summer months, but the ways in which climate change affects the risk of mosquito-borne diseases such as dengue, chikungunya, and Zika has remained somewhat mysterious . . .

 . . . The group found that mosquito traits favorable to spreading disease peaked when temperatures reached 29 degrees Celsius (84 degrees Fahrenheit), but were lower when temperatures were cooler or warmer.

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Bill Gates Won’t Save You From The Next Ebola

 Illustration of screens showing patients in a ward for Ebola patients. JI SUB JEONG/HUFFPOST

Image: Illustration of screens showing patients in a ward for Ebola patients. JI SUB JEONG/HUFFPOST

huffingtonpost.com - April 30th 2017 - Robert Fortner, Alex Park

In late August 2014, Tom Frieden, then director of the Centers for Disease Control and Prevention, traveled to West Africa to assess the raging Ebola crisis.

In the five months before Frieden’s visit, Ebola had spread from a village in Guinea, across borders and into cities in Liberia and Sierra Leone. Médecins Sans Frontières, the first international responder on the scene, had run out of staff to treat the rising numbers of sick people and had deemed the outbreak “out of control” back in June.

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