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Zika - Information, FAQs and Research

An expanding list of information resources on Zika virus . . .

CDC - Zika Virus - Case Counts in the US

CDC - Zika Virus - Timeline of "What's New"

CDC Newsroom Releases

Miami-Dade County Health Department

Newsroom - Miami-Dade County Health Department

Mosquito Control - Miami-Dade County

Broward County Health Department

Newsroom - Broward County Health Department

Florida Department of Health - Zika Virus - Daily Zika Updates

Florida Department of Health - Zika Virus

Texas Department of State Health Services - Zika in Texas

Brazil - Ministry of Health (MOH) - Situation Reports - Dengue, Chikungunya and Zika

Brazil - Ministry of Health

Columbia - Instituto Nacional de Salud (INS) - Zika 

WHO - Zika virus and potential complications: Questions and answers

WHO - Zika Situation Reports

WHO - Microcephaly / Zika virus

WHO - Zika virus

WHO - Zika Virus infection - Disease Outbreak News

WHO - Zika Open

WHO - Zika Outbreak: WHO's Global Emergency Response Plan

WHO - Prevention of potential sexual transmission of Zika virus - Interim Guidance - 18 February 2016 (2 page .PDF file)

WHO - Pregnancy management in the context of Zika virus - Interim guidance

WHO - Identification and management of Guillain-Barré syndrome in the context of Zika virus - Interim guidance

WHO - Detecting Guillain-Barré syndrome caused by Zika virus using systems developed for polio surveillance (8 page .PDF file)

WHO - Online First (scroll to the bottom)

WHO - Dispelling rumours around Zika and microcephaly

WHO - Prevention of sexual transmission of Zika virus - Interim guidance

WHO - Zika: the origin and spread of a mosquito-borne virus

WHO - Zika Causality Statement - 7 September 2016

PAHO / WHO - Zika Virus infection

U.S. DEPARTMENT OF STATE - Zika Virus Information for Travelers

CDC - Outcomes of Pregnancies with Laboratory Evidence of Possible Zika Virus Infection in the United States, 2016 - Pregnancy Outcomes in the United States and the District of Columbia

CDC - Zika virus

CDC - Zika Virus - Symptoms, Diagnosis, & Treatment

CDC - About Zika Virus Disease Q & A

CDC - Areas with Zika - Countries and territories with active Zika virus transmission

Map - Imported and locally acquired Zika virus in United States, territories, and Canada

Pacific Disaster Center - Zika Virus

CDC - Zika Travel Information

CDC - Zika virus disease in the United States, 2015–2016

CDC - Approved Lab Tests for Zika

CDC - Zika - Current National Biocontainment Laboratories and Regional Biocontainment Laboratories

CDC - Zika Virus - Vector Surveillance and Control

CDC - Surveillance and Control of Aedes aegypti and Aedes albopictus in the United States

CDC recommends the use of an EPA-registered insect repellent

EPA - Insect repellents

EPA - Insect repellent dataset (a link to the list is near the bottom)

EPA - Naled for Mosquito Control

CDC - REVISED - Zika - CDC Draft Interim #Response Plan (57 page .PDF report) - July 2016

CDC - Zika Virus Disease Q & A (Questions and Answers)

CDC - Build a Zika Prevention Kit

CDC - Zika - Fact Sheets & Posters

CDC - CDC Concludes Zika Causes Microcephaly and Other Birth Defects

CDC - Facts about Microcephaly

CDC - US Zika Pregnancy Registry

CDC - Emerging Infectious Diseases (EID) - Postmortem Findings in Patient with Guillain-Barré Syndrome and Zika Virus Infection

CDC - Emerging Infectious Diseases (EID) - Zika Virus RNA Replication and Persistence in Brain and Placental Tissue

CDC - Emerging Infectious Diseases (EID) - Detection of Zika Virus in Semen

CDC - Emerging Infectious Diseases (EID) - Prolonged Detection of Zika Virus in Vaginal Secretions and Whole Blood

CDC - Interim Guidelines for the Evaluation and Testing of Infants with Possible Congenital Zika Virus Infection — United States, 2016

CDC - Zika Virus Infection Among U.S. Pregnant Travelers — August 2015–February 2016

CDC - MMWR - Population-Based Surveillance of Birth Defects Potentially Related to Zika Virus Infection — 15 States and U.S. Territories, 2016

CDC - MMWR - Notes from the Field: Zika Virus-Associated Neonatal Birth Defects Surveillance — Texas, January 2016–July 2017

CDC - MMWR - Evaluation of Placental and Fetal Tissue Specimens for Zika Virus Infection — 50 States and District of Columbia, January–December, 2016

CDC - MMWR - Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy — U.S. Territories, January 1, 2016–April 25, 2017

CDC - MMWR - Vital Signs: Update on Zika Virus–Associated Birth Defects and Evaluation of All U.S. Infants with Congenital Zika Virus Exposure — U.S. Zika Pregnancy Registry, 2016 

CDC - MMWR - Preliminary Report of Microcephaly Potentially Associated with Zika Virus Infection During Pregnancy — Colombia, January–November 2016 

CDC - MMWR - Description of 13 Infants Born During October 2015–January 2016 With Congenital Zika Virus Infection Without Microcephaly at Birth — Brazil 

CDC - MMWR - Suspected Female-to-Male Sexual Transmission of Zika Virus — New York City, 2016 

CDC - MMWR - Notice to Readers: Changes in the Presentation of Zika Virus Disease, Non-Congenital Infection, and Addition of Zika Virus Congenital Infection to Notifiable Diseases and Mortality Table I 

CDC - MMWR - Interim Guidance for Zika Virus Testing of Urine — United States, 2016

CDC - MMWR - Update: Ongoing Zika Virus Transmission — Puerto Rico, November 1, 2015–April 14, 2016 

CDC - MMWR - Patterns in Zika Virus Testing and Infection, by Report of Symptoms and Pregnancy Status — United States, January 3–March 5, 2016 

CDC - MMWR - Notes from the Field: Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015

CDC - MMWR - Cluster of Ebola Virus Disease Linked to a Single Funeral — Moyamba District, Sierra Leone, 2014

CDC - MMWR - Update: Interim Guidance for the Evaluation and Management of Infants with Possible Congenital Zika Virus Infection — United States, August 2016

U.S. Department of Health and Human Services - Zika Virus Health Information Resource Guide

CIDRAP - Zika - Resources

NEJM - Zika Virus - Resources - clinical reports, guidelines, statement about sharing data in public health emergency

ProMED Mail - ZIKA VIRUS (23): AMERICAS - WHO overview, Cases in various countries, Zika virus genetics

Aedes aegypti - History of domestication and spread of Aedes aegypti - A Review

PLOS - Zika in the United States of America and a Fateful 1969 Decision

Aedes albopictus  - In the United States, it was initially found at the Port of Houston in a 1985 shipment of used tires

4 million at risk of Zika infection as El Niño increases spread

AJTMH - Vertical Transmission of Zika Virus in Aedes aegypti Mosquitoes

APJTM - Comparative genome analysis between Southeast Asian and South American Zika viruses

ASM - First Complete Genome Sequences of Zika Virus Isolated from Febrile Patient Sera in Ecuador

ATSMH - Double Threat: Researchers Find New Evidence Mosquitoes Could Infect Humans with Zika and Chikungunya Viruses at the Same Time 

ASTMH - Guillain–Barré Syndrome After Zika Virus Infection in Brazil

BioRxiv - Multiple introductions of Zika virus into the United States revealed through genomic epidemiology

BioRxiv - Genome sequencing reveals Zika virus diversity and spread in the Americas

BioRxiv - Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

BioRxiv - Zika virus may not be alone: proteomics associates a bovine-like viral diarrhea virus to microcephaly

BioRxiv - Dengue Virus Antibodies Enhance Zika Virus Infection

BioRxiv - Projected spread of Zika virus in the Americas

CID - Oxford Journals - Zika Virus Infection Associated With Severe Thrombocytopenia

eLIFE - Data-driven identification of potential Zika virus vectors

eLIFE - Mapping global environmental suitability for Zika virus

Emerging Infectious Diseases (EID) - Zika Virus Infection in Patient with No Known Risk Factors, Utah, USA, 2016

Emerging Infectious Diseases - CDC - EID - Real-Time Evolution of Zika Virus Disease Outbreak, Roatán, Honduras

Emerging Infectious Diseases - Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

Emerging Infectious Diseases - Zika Virus Transmission from French Polynesia to Brazil

Emerging Infectious Diseases - Health Precautions Taken by Travelers to Countries with Ebola Virus Disease

Emerging Infectious Diseases - CDC - EID - Inactivation and Environmental Stability of Zika Virus

Emerging Infectious Diseases - CDC - EID - Culex pipiens and Aedes triseriatus Mosquito Susceptibility to Zika Virus

Intensive Care Medicine - Key points on Zika infection for the intensivist 

Intensive Care Medicine - Zika virus-associated Guillain–Barré syndrome: a warning for critical care physicians

The Lancet - Anticipating the international spread of Zika virus from Brazil

International Journal of Infectious Diseases (IJID) - Unexpected and Rapid Spread of Zika Virus in The Americas - Implications for Public Health Preparedness for Mass Gatherings at the 2016 Brazil Olympic Games

Journal of Infectious Diseases - Outbreak of Zika virus infection, Chiapas State, Mexico, 2015, and first confirmed transmission by Aedes aegypti mosquitoes in the Americas (28 page .PDF file)

ECDC - Interim guidance for healthcare providers and Zika virus laboratory diagnosis

ECDC - Microcephaly in Brazil potentially linked to the Zika virus epidemic, ECDC assesses the risk

ECDC - (search - "Zika") 

ECDC - (search - "Microcephaly")



Gerontology - Zika Virus Infection in the Elderly: Possible Relationship with Guillain-Barré Syndrome

The Lancet - Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis 

The Lancet - Thrombocytopenia and subcutaneous bleedings in a patient with Zika virus infection 

The Lancet - Zika virus in semen of a patient returning from a non-epidemic area 

The Lancet - Zika virus in the female genital tract

The Lancet - Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation 

The Lancet - Zika: neurological and ocular findings in infant without microcephaly 

The Lancet - Microcephaly in Brazil: how to interpret reported numbers?

The Lancet - Zika virus and microcephaly: why is this situation a PHEIC? (3 page .PDF file)

The Lancet - Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

The Lancet - Acute myelitis due to Zika virus infection

The Lancet - Potential for Zika virus introduction and transmission in resource-limited countries in Africa and the Asia-Pacific region: a modelling study

The Lancet Infectious Diseases - Association between Zika virus infection and microcephaly in Brazil, January to May, 2016: preliminary report of a case-control study

JAMA - Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy 

JAMA - The Emerging Zika Pandemic - Enhancing Preparedness

JAMA Neurology - Neurologic Complications Associated With the Zika Virus in Brazilian Adults

JAMA Neurology - Enhanced Epilepsy Surveillance and Awareness in the Age of Zika

JAMA Pediatrics - Bridging Knowledge Gaps to Understand How Zika Virus Exposure and Infection Affect Child Development 

JAMA Pediatrics - What Does Zika Virus Mean for the Children of the Americas?

Journal of Global Infectious Diseases - The emergence of zika virus as a global health security threat: A review and a consensus statement of the INDUSEM Joint working Group (JWG);year=2016;volume=8;issue=1;spage=3;epage=15;aulast=Sikka

Journal of Infectious Diseases - Continued transmission of Zika virus in humans in West Africa, 1992-2016

Journal of Medical Entomology - Updated Reported Distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus (Diptera: Culicidae) in the United States, 1995–2016

mBio - Zika Virus Persistently Infects and Is Basolaterally Released from Primary Human Brain Microvascular Endothelial Cells

mBio - A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses

Nature - Establishment and cryptic transmission of Zika virus in Brazil and the Americas 

Nature - Genomic epidemiology reveals multiple introductions of Zika virus into the United States 

Nature - Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

Nature - A rhesus macaque model of Asian-lineage Zika virus infection

Nature Communications - Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Nature Communications - Neutralization mechanism of a highly potent antibody against Zika virus

Nature Communications - Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages

Nature Medicine - Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

Nature - Scientific Reports - Zika Virus in Salivary Glands of Five Different Species of Wild-Caught Mosquitoes from Mexico

Nature - Scientific Reports - A smartphone-based diagnostic platform for rapid detection of Zika, chikungunya, and dengue viruses

Nature - Scientific Reports - Zika virus infection induces mitosis abnormalities and apoptotic cell death of human neural progenitor cells

NECSI - The Case for Pyriproxyfen as a Potential Cause of Microcephaly; From Biology to Epidemiology

NECSI - A Possible Link Between Pyriproxyfen and Microcephaly

NEJM - Zika Virus Infection and Associated Neurologic Disorders in Brazil

NEJM - NEJM - Cutaneous Eruption in a U.S. Woman with Locally Acquired Zika Virus Infection

NEJM - BLOG - Zika Virus Infection in Pregnant Women in Rio de Janeiro 

NEJM - Zika Virus Infection in Pregnant Women in Rio de Janeiro

NEJM - Fatal Zika Virus Infection with Secondary Nonsexual Transmission 

NEJM - Zika and the Risk of Microcephaly 

NEJM - Zika Virus Disease in Colombia — Preliminary Report

NEJM - Zika Virus and Birth Defects — Reviewing the Evidence for Causality

NEJM - Review Article - Zika Virus

NEJM - BRIEF REPORT - Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities

NEJM - STUDY - Zika Virus Associated with Microcephaly

NEJM - EDITORIAL - Zika Virus and Microcephaly

NEJM - Zika Virus Infection in Pregnant Women in Rio de Janeiro — Preliminary Report

NEJM - Zika Virus as a Cause of Neurologic Disorders

NEJM - Zika Virus Associated with Meningoencephalitis

NEJM - Computed Tomographic Findings in Microcephaly Associated with Zika Virus

NEJM - Guillain–Barré Syndrome Associated with Zika Virus Infection in Colombia 

NEJM - Zika Virus and the Guillain–Barré Syndrome — Case Series from Seven Countries

NEJM - Uveitis Associated with Zika Virus Infection

Cell - Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys 

Cell - Zika Virus Infects Human Placental Macrophages

Cell Host & Microbe - Dynamics of Human and Viral RNA Methylation during Zika Virus Infection 

Cell Reports - Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears

Cell Reports - Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects

Cell Reports - Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia 

Cell - Wolbachia Blocks Currently Circulating Zika Virus Isolates in Brazilian Aedes aegypti Mosquitoes 

Cell - From Mosquitos to Humans: Genetic Evolution of Zika Virus

Cell Stem Cell (CSC) - Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection 

Cell Stem Cell (CSC) - Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

Cell - Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

Stem Cell Reports - Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection 

Opthalmology - Glaucoma and Congenital Zika Syndrome 

Peer J Preprints - Zika virus: A newly emergent vector-borne public health threat in the Americas

Peer J Preprints - Zika virus impairs growth in human neurospheres and brain organoids

Peer J - Estimating risks of importation and local transmission of Zika virus infection

PLOS - The potential economic burden of Zika in the continental United States

PLOS - Transmission of Zika virus through breast milk and other breastfeeding-related bodily-fluids: A systematic review 

PLOS - Zika: A scourge in urban slums 

PLOS - Prevalence of Antibodies to Zika Virus in Mothers from Hawaii Who Delivered Babies with and without Microcephaly between 2009-2012

PLOS - Vector Competence of American Mosquitoes for Three Strains of Zika Virus

PLOS - Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement

PLOS - Zika Virus Outbreak in Haiti in 2014: Molecular and Clinical Data

PLOS - Clinical and Epidemiological Characterization of Laboratory-Confirmed Autochthonous Cases of Zika Virus Disease in Mexico 

PLOS - On the Seasonal Occurrence and Abundance of the Zika Virus Vector Mosquito Aedes Aegypti in the Contiguous United States 

PLOS - Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal Demise

PLOS - Zika Virus Emergence in Mosquitoes in Southeastern Senegal, 2011

PLOS - Zika Virus in Gabon (Central Africa) – 2007: A New Threat from Aedes albopictus?

PNAS - Vulnerability of primitive human placental trophoblast to Zika virus

PNAS - Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast

PNAS - Zika virus cell tropism in the developing human brain and inhibition by azithromycin 

PNAS - Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus 

Zika and Microcephaly: How Doctors Made the Link

Physician Alert - Ultrasound in Obstetrics and Gynecology
Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg?

PBS - How does Zika virus shrink a baby’s brain and other FAQs 

Nature - Zika virus: Brazil's surge in small-headed babies questioned by report 

Aedes aegypti mosquitoes found in Washington D.C.

CDC - Isolation of Zika Virus from Febrile Patient, Indonesia

AJTMH - Zika Virus Infection Acquired During Brief Travel to Indonesia

Science - Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

Science - Countering Zika in Latin America

Science - The 3.8 Å resolution cryo-EM structure of Zika virus

Science - Zika virus in the Americas: Early epidemiological and genetic findings

Science - Don't blame sports for Zika's spread

Science Advances - Zika virus causes testicular atrophy

Science Beta - AXL May Be Zika Neural Stem Cell Entry Receptor - One year after the Zika virus outbreak in Brazil: from hypotheses to evidence - Guillain-Barré syndrome associated with the Zika virus outbreak in Brazil

ScienceDirect - Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

ScienceDirect - Zika virus: epidemiology, clinical features and host-virus interactions 

ScienceDirect - Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy 

(1 page .PDF file, with contact information near the bottom)

Volume 46 - Number 3 - May 2015 - Page 460

Texas Department of State Health Services (DSHS) - Zika in Texas

Texas DSHS - Texas Takes Aim at Zika Virus


Zika - List of Map Resources


Data Resources

Nature - Zika-microcephaly paper sparks data-sharing confusion 

WHO - Zika Open

HDX - Zika,+metadata_modified+desc#dataset-filter-start

Lancaster University - Zika



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