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Covid puzzle: They got sick, got treated, got covid again

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Crumley, like other patients who have experienced relapses after taking Paxlovid, is puzzled - and concerned. On Twitter, physicians and patients alike are engaged in a real-time group brainstorm about what might be happening, with scant evidence to work with.

It is the latest twist - and newest riddle - in the pandemic, a reminder that two years in, the world is still on a learning curve with the coronavirus.

Infectious-disease experts agree that this phenomenon of the virus rebounding after some patients take the drug appears to be real but rare. Exactly how often it occurs, why it happens and what - if anything - to do about it remain matters of debate.

What's clear is that patients should be warned it is possible so they don't panic - and so that they know to test again if they start feeling ill. More data is needed to understand what is going on. Paxlovid, made by the drug giant Pfizer, remains a useful drug, even though it has sparked a new mystery. ...

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