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New study outlines increased breakthrough case risks for pregnancy and other conditions

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A study published on Thursday found that pregnancy nearly doubles the risk of breakthrough COVID-19 cases, closely followed in risk by a solid organ transplant.

The study conducted by Wisconsin-based company Epic found that among the comorbidities that increase the risk of a breakthrough COVID-19 infection, pregnancy increased this risk the most by 1.91 times, which analyzed data from more than 140 million patients from 161 of the company’s organizations. 

Individuals were 1.83 times more likely to have a breakthrough COVID-19 infection if they had a solid organ transplant; those with an immune system deficiency were 1.63 times more at risk, according to the study.

Other comorbidities that increased the risk of a breakthrough infection, though to a lesser degree, included those who had kidney disease, liver disease or mental health issues, among others.

“These findings support the CDC’s recommendation that patients with a high-risk comorbidity may need to use enhanced infection prevention control beyond vaccination to minimize the risk of a COVID-19 breakthrough infection.”  ...

 

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