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WHO - Polio Outbreak Confirmed in Mali

                                            

afro.who.int

Bamako, 7 September 2015 – A case of circulating vaccine-derived poliovirus type 2 (cVDPV2) has been confirmed in Bamako, the capital and largest city of Mali. The country is on high alert after national authorities detected a paralysis case with onset 20 July 2015. The patient is a 19-month old child of Guinean nationality whose paralysis occurred 7 days prior to the child’s arrival in Bamako to seek health care. The last case of wild polio virus (WPV) in Mali dates back to June 2011 in Goundam, Timbuktu Region.

The current detected virus is genetically linked to a confirmed VDPV detected in Siguiri district, in the Kankan Region of Guinea in August 2014, and has been circulating across international borders for more than 2 years without detection. 

The risk of spread of this virus is deemed high and it has the capacity to cause paralytic disease in humans or kill. The emergence and circulation of VDPV2 reveals low population immunity against the virus due to low rates of vaccination coverage in Guinea. Consequently, oral polio vaccine (OPV) must be administered multiple times to stop the outbreak and protect children. 

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WHITE HOUSE FACT SHEET: The Global Health Security Agenda

The U.S. Government announces it intends to invest more than $1 billion in resources to expand the Global Health Security Agenda to prevent, detect, and respond to future infectious disease outbreaks overseas.

THE WHITE HOUSE PRESS OFFICE                       July 28, 2015

The Ebola epidemic in West Africa continues to galvanize global attention and resources as the international community strives to eliminate active cases and help the affected countries recover.  African leaders and African Union officials have shown extraordinary leadership in addressing the outbreak. The epidemic highlighted the urgent need to establish global capacity to prevent, detect, and respond to biological threats – to prevent future outbreaks from becoming epidemics. 

Beginning with the release of the National Strategy for Countering Biological Threats in 2009, and outlined in his 2011 speech at the United Nations General Assembly, President Obama has called upon all countries to come together to prevent, detect, and respond to infectious disease threats, whether naturally occurring, accidental or deliberately spread.  Today, the President underscored the unwavering U.S. commitment to partnering with Africans, their governments, and all who will join the effort to improve health security across the continent and for all people.

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Ebola virus not mutating as quickly as thought

SCIENCE NEWS  by Ashley Yaeger                                                      March 26, 2015

(Scroll down for full study.)

The virus causing the current Ebola epidemic in West Africa is not evolving as quickly as some scientists had suggested.

REGULAR RATE  A genetic analysis suggests that the Ebola virus, shown here in orange, is not evolving as fast as expected.

In a paper last August, researchers reported that the virus (Zaire ebolavirus) was altering its genes almost twice as fast as it had during previous Ebola outbreaks in Central Africa (SN: 9/20/14, p. 7). However, a new genetic analysis shows that the virus is mutating at roughly the same rate as in past outbreaks, researchers report online March 26 in Science. The finding suggests the virus has not become more virulent or transmissible during the West Africa outbreak.

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The case for EOCs post-Ebola

DEVEX    by  By Jenny Lei Ravelo                        March 19, 2015
Emergency operation centers have been critical in stemming potential Ebola outbreaks in several West African countries like Nigeria and Mali, but there remain doubts about whether countries would keep them post-Ebola. Ismail Ould Cheikh Ahmed, special representative of the secretary-general and head of the U.N. Mission for Ebola Emergency Response, meets with UNMEER staff at the Ebola Operation Center in Bamako, Mali. Should EOCs be retained post-Ebola? Photo by: Pierre Peron / UNMEER / CC BY-ND

This is largely because of its potential to cause “institutional turf wars” within the government structure, according to Madji Sock, partner at global development advisory firm Dalberg.

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First look at hospitalized Ebola survivors' immune cells could guide vaccine design

MEDICALXPRESS                                                                                                 March 9, 2015
Researchers from Emory and the Centers for Disease Control and Prevention have now obtained a first look at the responses in four Ebola disease survivors who received care at Emory University Hospital in 2014, by closely examining their T and B cells during the acute phase of the disease. The findings reveal surprisingly high levels of , and have implications for the current effort to develop vaccines against Ebola.

The Ebola virus, isolated in November 2014 from patient blood samples obtained in Mali. The virus was isolated on Vero cells in a BSL-4 suite at Rocky Mountain Laboratories. Credit: NIAID

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Botswana Doctor Is Named to Lead W.H.O. in Africa

NEW YORK TIMES  by Donald G. McNeil, Jr.                                                               Jan. 27, 2015

A defining moment in the life of Dr. Matshidiso Moeti, the World Health Organization’s new regional director for Africa, came when she was 9 and her father realized that her little sister’s mathematics textbook was below even the level he had studied as a poor child on a South African farm.

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Mali government, UN declare country Ebola-free

AFP                                                                Jan. 18, 2015

BAMAKO - The Malian government and the United Nations on Sunday declared the country free of Ebola after 42 days without any new cases of the deadly virus.

A man washes his hand in the village of Kouremale, Mali, to help prevent the spread of Ebola.

Health Minister Ousmane Kone said no confirmed cases had been registered since December 6 when the last Ebola patient had tested negative.

The west African country "had come out" of the epidemic, Ibrahima Soce Fall, the head of the Malian office of the United Nations Mission for Ebola Emergency Response (UNMEER), confirmed.

Health Minister Ousmane Kone said no confirmed cases had been registered since December 6 when the last Ebola patient had tested negative.

Read complete story.

http://news.yahoo.com/mali-government-un-declare-country-ebola-free-221318115.html

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Ebola in West Africa: 12 months on

WORLD HEALTH ORGANIZATION MEDIA CENTRE                   Jan, 15, 2015

One year after the first Ebola cases started to surface in Guinea, WHO is publishing this series of 14 papers that take an in-depth look at West Africa’s first epidemic of Ebola virus disease.

The papers explore reasons why the disease evaded detection for several months and the factors, many specific to West Africa, that fuelled its subsequent spread.

The most extensive papers trace events in each of the 3 most severely affected countries – Guinea, Liberia and Sierra Leone...

Key events are set out chronologically, starting with the child who is believed to be the index case of this epidemic through to the Director-General’s commitment to steadfastly support affected countries until they reach zero cases.

Read complete news release

http://www.who.int/mediacentre/news/notes/2015/ebola-one-year-on/en/
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Read report:

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Travelers from Mali no longer need to go through enhanced Ebola screenings

WASHINGTON POST    by Marc Berman                                                  Jan. 5, 2015

People flying to the United States from Mali will no longer need to go through enhanced Ebola screening at U.S. airports, authorities announced Monday.

An interview with a passenger arriving from a country with known instances of Ebola. (Josh Denmark/U.S. Customs and Border Protection via Reuters)

The change, which goes into effect Tuesday, also means that people flying from Mali no longer have to travel through the five U.S. airports that use the screening methods. Travelers from Mali will continue to be screened before leaving that country, and anyone who flew from Mali to the United States before Tuesday is still supposed to monitor themselves for 21 days and report symptoms.

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Ebola in Graphs: The toll


THE ECONOMIST                                                                                                    Jan. 1, 2015
THE first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak. The numbers keep climbing. As of December 28th, 20,206 cases and 7,905 deaths had been reported worldwide, the vast majority of them in these same three countries. Many suspect these estimates are badly undercooked.
See complete set of graphs.
http://www.economist.com/blogs/graphicdetail/2015/01/ebola-graphics

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