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Fresh Graves Point to Undercount of Ebola Toll

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London Group Plans to Start First Clinical Tests of Ebola Drugs in West Africa

Washington Post

by Abby Ohlheiser September 23 at 11:45 AM

London based scientists, working with international aid groups, are planning to start the first clinical trials in West Africa for drugs to treat Eboa. The trials could begin in a matter of months.

Wellcome Trust's $5 million initiative will include drugs from Mapp Biopharmaceutical, Sarepta and Tekmira, according to Reuters. Mapp makes zMapp, the experimental cocktail administered to two Americans who contracted the disease in Liberia. Tekmira recently gained the approval of the U.S. Food and Drug Administration to use its TKM-Ebola treatment on confirmed or suspected cases of the disease.

Both drugs are still in the experimental phase; researchers have not yet determined the safety or effectiveness of the treatments.

Text of full story:

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EBOLA MAY BECOME ENDEMIC TO WEST AFRICA WITH 71 PER CENT INFECTION RATE--WHO STUDY

LOS ANGLES TIMES     September 22, 10:25 PM

by Monte Morin

In a grim assessment of the Ebola epidemic, researchers say the deadly virus threatens to become endemic to West Africa instead of eventually disappearing from humans.

"The current epidemiologic outlook is bleak," wrote a panel of more than 60 World Health Organization experts in a study published Tuesday by the New England Journal of Medicine.

"We must therefore face the possibility that Ebola virus disease will become endemic among the human population of West Africa, a prospect that has never previously been contemplated."

In the absence of new control measures, the authors estimated that the total case load would exceed 20,000 by Nov 2.

Link to full story

http://www.latimes.com/science/sciencenow/la-sci-sn-ebola-may-be-endemic-in-people-20140922-story.html

Link to New England Journal of Medicine study

http://www.nejm.org/doi/full/10.1056/NEJMoa1411100?query=featured_ebola

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World wakes up to Ebola as cases set to top 1 million

By Debora MacKenzie - 23 Sep 2014 - newscientist.com

This article appeared in print under the headline "World wakes up to true threat of Ebola"

Only decisive action can stop the virus becoming entrenched in Africa and spreading elsewhere, say epidemiologists.

The world has finally got serious about Ebola. In a first for a public health threat, the United Nations has launched the kind of response it normally reserves for war zones. Meanwhile, the US, UK and France are sending troops to build treatment units, train health workers and keep order.

It's not a moment too soon: the US Centers for Disease Control and Prevention warn that without a massive effort to slow the epidemic, a million people in West Africa could have Ebola by January. Some will carry it elsewhere, and the virus may circulate non-stop in Africa for the foreseeable future.

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WHO PLAN WOULD MOVE INFECTED PERSONS FROM HOMES TO COMMUNITY CENTERS

Washington Post  September 23, 014
by Lenny Bernstein and Lena H. Sun

MONROVIA, LIBERIA  -The Liberian government, the World Health Organization and their nonprofit partners here are launching an ambitious but controversial program to move infected people out of their homes and into ad hoc centers that will provide rudimentary care, officials said Monday.

The community centers would supplement hospitals.

However Doctors Without Borders Director of operations says "this is not going to work," saying the infected countries do not have the needed infrastructure.

http://www.washingtonpost.com/national/health-science/new-effort-to-fight-ebola-in-liberia-would-move-infected-patients-out-of-their-homes/2014/09/22/f869dc08-4281-11e4-b47c-f5889e061e5f_story.html?hpid=z5

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Get Smarter on Agriculture and Climate

David Cleary Director of Agriculture Nature ConservancyBy David Cleary - Sep 22, 2014 - environmentalleader.com

In a somber scene-setter for the upcoming climate summit in New York, the UN’s meteorological office, The World Meteorological Organization, released a report showing that world carbon emissions in 2013 reached a record high, and atmospheric carbon is increasing at the fastest rate seen in over thirty years. Some hard questions are facing the international order, which has spent much of that period in an interminable round of meetings meant to combat climate change. Against this backdrop, the pertinent question the UN report raises is: why bother? If we appear to be losing the battle, what difference does yet another meeting and round of press conferences make, other than to traffic conditions in lower Manhattan?

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Ban Ki-moon: 'World living in an era of unprecedented level of crises'

United Nations secretary general Ban Ki-moon with actor Leonardo DiCaprio during his designation ceremony as the UN Messenger of Peace. Photograph: EPA

United Nations secretary general Ban Ki-moon with actor Leonardo DiCaprio during his designation ceremony as the UN Messenger of Peace. Photograph: EPA

Julian Borger - New York The Guardian
21 Sep 2014 16.55 BST

More than 140 heads of state and government fly in to New York this week for the United Nations general assembly amid apprehension that international order is unraveling at an accelerating pace, while the world's leaders seem ever less willing or able to deal with the proliferating threats.

The UN's humanitarian agencies are in danger of being completely overwhelmed by the multiple crises. Ebola is spreading rapidly across West Africa, swamping rickety national health systems and a thus-far underfunded UN effort to stop its advance. The spread of Islamic State (Isis) extremists in the Middle East, feeding on the destruction of the Syrian civil war and exposing the weakness of the Iraqi state, has similarly outpaced patchy international efforts at containment.

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Ebola in Africa: Chaos is contagious

Illustration: Ebola virus (Photo: Thinkstock.com)courier-journal.com/The Chigaco Tribune - Sep 22, 2014

Faced with a brutal and wily adversary, President Barack Obama on Tuesday ordered a scaled-up military assault. Not on terrorists in Syria, but Ebola in West Africa.

The president dispatched some 3,000 American troops to help build 17 treatment centers. The Pentagon will establish a military command center in Liberia to coordinate the civilian response to the epidemic. American military health experts will help train thousands of African health care workers. American aid workers will help distribute supplies and information to families there.

The U.S. — and, we hope, the rest of the world — is getting serious about confronting this plague blazing through Africa. The official Ebola toll as of late Tuesday: 4,985 cases and 2,461 deaths. Some experts, however, suspect the actual death tally is much higher. And the rate of Ebola infection is growing exponentially. The number of Ebola cases could spike to 20,000 in a matter of months.

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Searching for the answer: Can the world stop Ebola?

By Elizabeth Cohen - Sep 22, 2014 - cnn.com

Monrovia, Liberia (CNN) -- As I stood in the sweltering heat outside the Centers for Disease Control and Prevention in Atlanta earlier this week, President Barack Obama whispered in my ear.

Okay, he didn't exactly whisper, and his words were intended not just for me. In one of the most significant addresses of his presidency, Obama declared to the world that he would send 3,000 troops to Ebola-stricken West Africa.

Obama's speech was being piped into my earpiece, and I was about to go on CNN when I picked up my phone and emailed my friend Jake Tapper, the host of the show.

"World knows how to fight this disease," I wrote in the subject line, quoting the words I had just heard Obama speak.

After getting off the plane, Elizabeth Cohen has her temperature taken, since a fever is one symptom of Ebola. Her temperature was normal.

In the body of the email, I wrote to Jake, "Does it?"

And that's why I took an airplane to Liberia. I want to answer my own question.

(READ COMPLETE ARTICLE)

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Life under Ebola quarantine – in pictures

Photograph: Rein Skullerud/WFPtheguardian.com - 22 September 2014

As health authorities attempt to halt the spread of Ebola in Liberia, many citizens are struggling to feed themselves. People who have lost members of their household to the virus are often confined to their homes for weeks, making it difficult to collect food and other essentials. The UN World Food Programme (WFP) is distributing food to families in quarantine in 10 counties across Liberia

http://www.theguardian.com/global-development/gallery/2014/sep/22/life-under-ebola-quarantine-in-pictures

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